clinical trial · NCT06919991
Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)
Healthy ParticipantsCasdatifanItraconazolePhenytoin
brief summary
The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in healthy adults and to assess the effects of multiple doses of phenytoin (a strong CYP3A4 inducer) on single dose PK of casdatifan in healthy adults.
started
May 2, 2025
primary completion
Oct 18, 2025
completion
Oct 18, 2025
last updated
Nov 13, 2025
official title
A Phase 1, Open-Label, Fixed-Sequence, Drug-Drug Interaction Study of Casdatifan With Itraconazole (Strong CYP3A4 Inhibitor) and Phenytoin (Strong CYP3A4 Inducer) in Healthy Adult Participants
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol