clinical trial · NCT06736691
Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections
Swiss Tropical & Public Health Institute·phase3·enrolling by invitation·n = 315
Trichuris Trichiura; InfectionHookworm InfectionAscaris Lumbricoides Infectionemodepside (BAY 44-4400)matching placebo of emodepsideMebendazolesimilar placebo to mebendazole
brief summary
This study aims to assess the efficacy and safety of emodepside compared to mebendazole in adults and adolescents infected with T. trichiura, either as single infection or co-infections with hookworm and/or A. lumbricoides.
started
Nov 25, 2025
primary completion
May 1, 2026
completion
Jul 1, 2026
last updated
Jan 7, 2026
official title
A Phase III Single-center, Randomized, Double-blinded, Parallel-group, Active-controlled Study to Evaluate the Efficacy and Safety of a Single Dose of Emodepside Compared to Multiple Doses of Mebendazole in Adolescent and Adult Participants With Soil-transmitted Helminthiasis
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol