clinical trial · NCT06724978
A Study of S-740792 in Healthy Adult Study Participants
Shionogi·phase1·completed·n = 99
Healthy ParticipantsS-740792 SuspensionMidazolamPlaceboS-740792 Tablet
brief summary
This is a 3-part study of S-740792 in healthy adult participants. Part 1 (single-ascending-dose and food effect) will investigate the safety, tolerability, and pharmacokinetics (PK) of S-740792. Part 2 (multiple-ascending-dose and drug-drug interaction) will investigate the safety, tolerability, and PK of S-740792, in addition, the effect of multiple doses of S-740792 on the PK of midazolam. Part 3 will investigate the relative bioavailability of S-740792 tablet compared to S-740792 suspension and the food effect on the PK of the S-740792 tablet.
started
Nov 21, 2024
primary completion
Sep 10, 2025
completion
Sep 24, 2025
last updated
Oct 2, 2025
official title
A Phase 1 Single- and Multiple-ascending-dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of S-740792 in Healthy Adult Study Participants
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol