clinical trial · NCT06724900
A Study Assessing KB304 for the Treatment of Wrinkles in Women
Wrinkles in DecolletagePigmentationDécolleté WrinklesKB3040.9% Normal Saline (NS)
brief summary
The aim of this study is to investigate the safety and efficacy of KB304, an investigational gene therapy to correct moderate to severe wrinkles in the décolleté region (V-shaped chest area). KB304 is an investigational gene therapy that delivers functional, full-length human collagen (COL3) and elastin (tropoelastin) to the skin through small injections using the Sponsor's genetically engineered Herpes Simplex Virus (HSV-1) vector. The study is a randomized double-blind study and participants will receive either KB304 (active group) or placebo (inactive group).
started
Nov 20, 2024
primary completion
Jul 1, 2025
completion
Aug 1, 2025
last updated
May 13, 2025
official title
A Phase 1/2 Study of KB304, a Replication-Defective, Non-Integrating Vector Expressing Human Type III Collagen (COL3) and Tropoelastin for the Treatment of Wrinkles
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol