clinical trial · NCT06719557
A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008)
Merck Sharp & Dohme LLC·phase1·completed·n = 28
HealthyCalderasibItraconazolePhenytoin
brief summary
The goal of this study is to learn what happens to calderasib in a healthy person's body over time, called a pharmacokinetic (PK) study. Researchers want to compare the amount of calderasib when it is taken as a single dose; with multiple doses of itraconazole, or with multiple doses of phenytoin.
started
May 20, 2024
primary completion
Jul 30, 2024
completion
Jul 30, 2024
last updated
Feb 11, 2026
official title
A Two-Part Study to Evaluate the Effects of Multiple Doses of Itraconazole and Multiple Doses of Phenytoin on the Single-Dose Pharmacokinetics of MK-1084 in Healthy Adult Participants
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol