clinical trial · NCT06671093
Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B
Tune Therapeutics, Inc.·phase1·recruiting·n = 36
Chronic Hep BChronic Hepatitis bChronic HepatitisHBVTune-401
brief summary
This study will be conducted to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Tune-401 in adult participants with Chronic Hepatitis B.
started
Nov 29, 2024
primary completion
Jun 28, 2028
completion
Oct 30, 2028
last updated
Jan 6, 2026
detailed description
This study consists of an open-label, Part I single-ascending dose phase and Part II single and finite multiple dose phase to characterize the activity of Tune-401 on PD parameters and obtain safety data.
official title
Phase 1b Multicenter, Open-Label Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Tune-401 in Participants With Chronic Hepatitis B Infection
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol