clinical trial · NCT06632613
Efficacy and Safety of ENN0403 in Patients At High Risk for Acute Kidney Injury Following Elective Cardiac Surgery
Cardiac Surgery Associated - Acute Kidney InjuryENN0403 capsules, low doseENN0403 capsules, high dosePlacebo
brief summary
The is a two-stage study. Stage 1 is to evaluate the safety, tolerability, PK and PD of ENN0403 in patients at high risk of AKI following elective cardiac surgery requring cardiopulmonary bypass. Stage 2 is to evaluate the efficacy, safety, PK and PD of ENN0403 to prevent and treat AKI after multiple administraions in patients at high risk of AKI following elective cardiac surgery requring cardiopulmonary bypass.
started
Nov 5, 2024
primary completion
Feb 1, 2026
completion
Mar 1, 2026
last updated
Jan 13, 2025
official title
A Phase 2 Clinical Study Evaluating the Efficacy and Safety of ENN0403 in Patients At High Risk for Acute Kidney Injury Following Elective Cardiac Surgery Requiring Cardiopulmonary Bypass
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol