clinical trial · NCT06397560
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial
Baptist Health South Florida·N/A·recruiting·n = 28
GliomaGlioma, MalignantRecurrent GliomaPRDR
brief summary
The purpose of this research study is to see if a specific type of radiation therapy, called "proton pulsed reduced dose rate" or "PRDR radiotherapy" has any benefits at dose levels and number of fractions thought to be acceptable in earlier research studies. The researchers want to find out what effects (good and bad) PRDR has on people with cancer in the brain called a "recurrent high-grade glioma" meaning that it grows fast, can spread quickly, and it has come back or gotten worse after being treated previously.
started
Apr 30, 2025
primary completion
Sep 1, 2028
completion
Jun 1, 2029
last updated
Jun 27, 2025
official title
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies (POPCORN) Trial
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol