clinical trial · NCT05848687
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Tanja Andrea Gruber·phase2·recruiting·n = 90
Lymphoblastic LeukemiaDexamethasoneMitoxantronePEG asparaginaseBortezomibVorinostatMercaptopurineMethotrexateBlinatumomab
brief summary
The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia cells outer membrane.
started
Nov 3, 2023
primary completion
Dec 1, 2028
completion
Dec 1, 2033
last updated
Apr 20, 2026
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol