clinical trial · NCT05820841
Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell Lymphoma
Universität des Saarlandes·phase3·recruiting·n = 330
Large B-cell LymphomaDiffuse Large B Cell LymphomaR-miniCHOP + AcalabrutinibR-miniCHOP
brief summary
The goal of this clinical trial is to study the addition of Acalabrutinib to standard R-miniCHOP in older adults with DLBCL. The main question it aims to answer is whether progression free survival kann be prolonged with the addition of Acalabrutinib. Participants will be randomised to receive either R-miniCHOP alone or R-miniCHOP with Acalabrutinib.
started
Jun 7, 2023
primary completion
Apr 1, 2028
completion
Dec 1, 2028
last updated
Aug 31, 2023
official title
A Randomized, Open-label, Phase 3 Study of Acalabrutinib in Combination With Rituximab and Reduced Dose CHOP (R-miniCHOP) in OldEr Adults With Untreated Diffuse Large B-Cell Lymphoma
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol