clinical trial · NCT05642455
SPEARHEAD-3 Pediatric Study
USWM CT, LLC·phase2·recruiting·n = 20
Synovial SarcomaMalignant Peripheral Nerve Sheath Tumor (MPNST)Neuroblastoma (NBL)OsteosarcomaAfamitresgene autoleucel
brief summary
This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.
started
Sep 1, 2023
primary completion
Oct 1, 2026
completion
Jul 30, 2038
last updated
Feb 9, 2026
official title
A Phase 1/2 Open Label, Basket Study to Assess the Safety, Tolerability and Anti-Tumor Activity of Afamitresgene Autoleucel in Pediatric Subjects With MAGE-A4 Positive Tumors
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol