clinical trial · NCT05593666
A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis
Drugs for Neglected Diseases·phase2·active not recruiting·n = 101
Primary Visceral LeishmaniasisLXE408PlaceboAmBisome®
brief summary
This is a phase II, multicentre, randomized, two-arm blinded study with an open label calibrator arm in adults and adolescents (≥12 years) with confirmed primary VL.
started
Dec 27, 2022
primary completion
Apr 15, 2025
completion
Dec 30, 2025
last updated
Dec 18, 2025
detailed description
This study is run by DNDi with Novartis as co-development partner
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol