clinical trial · NCT05302531
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome
Central Hospital, Nancy, France·phase1·recruiting·n = 10
Short Bowel SyndromeInfection, BacterialAmoxicillinLevofloxacinOfloxacinSulfamethoxazole trimethoprim
brief summary
The purpose of this study is to assess the drug absorption of oral antibiotics in patients with short bowel syndrome.
started
Dec 9, 2022
primary completion
Dec 1, 2024
completion
Feb 1, 2025
last updated
Aug 29, 2024
detailed description
When required, due to an infection, patients with short bowel syndrome will be treated with an intravenous antibiotic. The pharmacokinetic profile of that intravenous antibiotic will be determined. Once the full treatment with the intravenous antibiotic is over, the patient will be orally administered the same antibiotic, with determination of the oral pharmacokinetic profile, and both profiles will be compared, assessing the bioavailability of the oral antibiotic.
official title
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome : a Monocentric Pilot Study
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol