clinical trial · NCT05090267
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
CognitionGut MicrobiomeProbiotic SupplementTranscutaneous Vagal Nerve Stimulation (tVNS)
brief summary
This project uses a hybrid trial design to evaluate two biomedical interventions targeting the gut-brain axis. One intervention is portable Transcutaneous Vagus Nerve Stimulator, tVNS, that is hypothesized to stimulate the autonomic nervous system, resulting in decreased inflammation and improved cognition. The second intervention is a probiotic supplement intended to replace gut bacteria that are associated with dysbiosis in persons with HIV and alcohol consumption.
started
Jun 1, 2022
primary completion
Dec 30, 2026
completion
Dec 30, 2026
last updated
Aug 6, 2026
official title
Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol