clinical trial · NCT04606537
Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects
HealthyDrug Drug InteractionItraconazoleRifampinKBP-5074
brief summary
Open-label, parallel, 2-arm, fixed-sequence study to investigate the effect of coadministration of a CYP3A4 inhibitor (Cohort 1, itraconazole multiple dose) and CYP3A4 inducer (Cohort 2, rifampin multiple dose) on the plasma PK of a single dose of KBP-5074 in healthy male and female subjects.
started
Oct 24, 2020
primary completion
Nov 30, 2020
completion
Nov 30, 2020
last updated
Dec 16, 2025
official title
Phase 1, Open-label, Parallel, 2-arm, Fixed-sequence Study to Investigate the Effect of Coadministration of CYP3A4 Inhibitor and CYP3A4 Inducer on the Pharmacokinetics, Safety, and Tolerability of KBP-5074 in Healthy Subjects
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol