Open-Label Surufatinib in European Patients With NET
brief summary
This is a Phase 2, open-label, multi-centre study of surufatinib in patients with low to intermediate grade (Grade 1 or Grade 2), well-differentiated neuroendocrine tumours (NETs).
detailed description
This is a Phase 2, open-label, multi-centre study of surufatinib in patients with low- to intermediate-grade (Grade 1 or Grade 2), well-differentiated NETs.
The study will enroll 4 cohorts of varying NETs, as follows:
* Cohort A - NET of lung origin * Cohort B - NET of small bowel origin * Cohort C - NET of non-small bowel, non-pancreas, and non-lung origin * Cohort D - NET of any origin (DDI substudy)
All patients will be treated with oral surufatinib 300 mg QD in treatment cycles of 28 days starting on Cycle 1 Day 1.
official title
An Open-Label Phase 2 Study of Surufatinib in Patients With Neuroendocrine Tumours in Europe