clinical trial · NCT04410965
Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chinese RMS Patients Treated With Teriflunomide 14 mg Once Daily for 24 Weeks
Multiple SclerosisTERIFLUNOMIDE
brief summary
Primary Objective: Evaluate the relationship between ABCG2 mutation (rs2231142) and teriflunomide exposure, during 6-month treatment with teriflunomide 14 mg Secondary Objective: Characterize the safety (AEs, such as ALT enhancement, hair thinning, diarrhea, nausea, etc.) during 6-month treatment with teriflunomide
started
May 20, 2020
primary completion
Jul 12, 2021
completion
Jul 12, 2021
last updated
Sep 24, 2025
detailed description
Study duration per participant is approximately 28 weeks including a 24-week treatment period
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol