clinical trial · NCT03604692
A Phase 1/2 Study to Evaluate Axatilimab in Participants With Active cGVHD
Chronic Graft-versus-host-diseaseaxatilimab
brief summary
This is a Phase 1/2, Open-label, Dose Escalation study to investigate axatilimab in participants with active chronic graft versus host disease (cGVHD).
started
Nov 1, 2018
primary completion
Aug 12, 2022
completion
Oct 18, 2024
last updated
Sep 15, 2025
detailed description
This is a dose escalation and dose expansion study in participants with active cGVHD who have received at least 2 lines of prior therapy.
official title
A Phase 1/2, Open-Label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamic Activity, and Efficacy of SNDX- 6352 in Subjects With Active Chronic Graft Versus Host Disease Who Have Received at Least 2 Lines of Prior Therapy
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol