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  • Sanofi books over €1 billion impairment after ending eczema drug and halting two immunology programs
    Sanofi disclosed that it will record more than €1.03 billion in impairment charges for the second quarter. The bulk of the charge stems from the decision to terminate development of an eczema trea…
    Endpoints · 4h agoNegative↗ source
  • Johnson & Johnson prepares $2.58 billion option to acquire Sail Biomedicines, expanding in-vivo CAR-T portfolio
    Johnson & Johnson announced a $2.58 billion option agreement to purchase Sail Biomedicines, a Flagship Pioneering‑backed biotech focused on in‑vivo CAR‑T therapies. The deal includes an upfront pa…
    Endpoints · 9h agoDealNeutral↗ source
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  • J&J invests $785M in Sail Biomedicines, secures option to buy for $2.58B
    Johnson & Johnson has agreed to pay $785 million up front to Sail Biomedicines, including a $465 million equity infusion and up to $140 million in milestone payments. The agreement also gives J&J a…
    Fierce Biotech · 11h agoDealPositive↗ source
  • FDA panel rejects Capricor's Duchenne drug, citing insufficient efficacy data
    The U.S. Food and Drug Administration advisory committee voted 9-to-3 against a Capricor Therapeutics candidate for Duchenne muscular dystrophy. The panel said the clinical data did not provide sub…
    STAT · 1h agoRegulatoryNegative↗ source
  • Ebola cases approach key milestone as vaccine candidates draw near completion
    The latest update on the Ebola outbreak indicates that the number of cases is approaching a significant threshold, while vaccine development efforts are reported to be close to delivering a usable…
    STAT · 2h agoNeutral↗ source
  • Sanofi’s new CEO vows deeper review of late-stage pipeline after series of trial failures
    Sanofi appointed Belén Garijo as chief executive in February with a clear mandate to tighten R&D governance and boost productivity. The board tasked her with bringing more rigor to the company’s st…
    Fierce Biotech · 9h agoNegative readoutNegative↗ source
  • FDA advisory panel reviews Replimune's experimental melanoma therapy RP1
    STAT is live-blogging an FDA Cellular, Tissue, and Gene Therapies Advisory Committee meeting that convened on Thursday to examine Replimune's engineered viral immunotherapy RP1 for melanoma. The p…
    STAT · 4h agoRegulatoryNeutral↗ source
  • Opinion: Ten years after WHO recognition, mycetoma remains one of the world’s most neglected diseases
    “The next 10 years of mycetoma care will determine whether it remains a story of neglect or becomes one of collective action,” writes Borna Nyaoke-Anoke.
    STAT · 5h agoRegulatoryNeutral↗ source
  • Experts warn U.S. pharma reliance on China poses national security threat
    The authors of a recent Council on Foreign Relations report argue that the United States’ dependence on China for biopharmaceutical manufacturing creates a clear national security risk. They point…
    STAT · 5h agoNegative↗ source
  • Medicaid work rules spark confusion over medically frail exemption, risking coverage for chronically ill
    Nebraska will begin enforcing Medicaid work requirements next week, demanding that beneficiaries work, volunteer or attend school for at least 80 hours each month or risk losing their health covera…
    STAT · 5h agoRegulatoryNegative↗ source
  • Red Bull-funded studies downplay risks of mixing energy drinks with alcohol, shaping policy despite independent warnings
    An investigative report found that research funded by the energy‑drink maker contradicted the bulk of independent studies on the dangers of combining alcohol with caffeinated beverages. The funded…
    STAT · 10h agoRegulatoryNegative↗ source
  • Key Senate panel backs Trump’s picks for CDC, pandemic preparedness
    In win for RFK Jr., Senate committee sends nominations of Erica Schwartz for CDC director and Sean Kaufman for ASPR to full Senate.
    STAT · 9m ago↗ source
  • Ipsen has 'firepower' for more deals with €2B war chest
    Ipsen has its eyes trained on more M&A — and has €2 billion worth of “firepower” to do it, based on its cash position at the end of June, CFO Aymeric Le Chatelier said. “If we ...
    Endpoints · 10m ago↗ source
  • Judge denies states’ motion to postpone Medicaid work requirement
    Federal judge denied 26 states’ request to postpone the implementation of Medicaid work requirements announced in June.
    STAT · 41m ago↗ source
  • Gerresheimer divests two businesses worth €1.5B; Resilience, Lilly boost injectable pen capacity
    Plus, news about Teva. 💶 Gerresheimer sells two subsidiaries to private equity: Gerresheimer is divesting its Centor and Primary Packaging Plastics (PPP) businesses to private equity firm Apax Par…
    Endpoints · 56m ago↗ source
  • Alnylam cuts Amvuttra sales guidance as demand shifts, hurting stock
    Alnylam’s second-quarter earnings report Thursday did little to assuage investor concerns in what has already been a difficult year for the company. The drugmaker lowered its full-year sales sales…
    Endpoints · 1h ago↗ source
  • STAT+: Rising oil prices can boost the cost of some medicines. One expert says it’s time to lower reliance on fossil fuels
    Unitaid found the rising price of oil could boost the cost of a widely used HIV medicine it reviewed in a detailed analysis.
    STAT · 1h ago↗ source
  • Relation promises 'transformationally different success rates' in expanded AI pact with GSK
    GSK is set to pay Relation Therapeutics up to $110 million to expand their existing partnership to use AI modeling for drug discovery. Under the Thursday deal, Relation will build a ...
    Endpoints · 3h ago↗ source
  • Bristol Myers delays Cobenfy Alzheimer’s psychosis readout again amid another quarterly beat
    Investors awaiting Bristol Myers Squibb’s key Alzheimer’s psychosis readout for Cobenfy and atrial fibrillation data for milvexian will have to wait a little longer.
    Fierce Biotech · 4h ago↗ source
  • Attovia, Braveheart and Vogenx seek more than $500M across trio of IPOs
    Attovia Therapeutics, Braveheart Bio and Vogenx have set target ranges for their IPOs, positioning the trio to collectively net more than $500 million from public investors.
    Fierce Biotech · 5h ago↗ source
  • Labcorp posts higher Q2 earnings on strength of diagnostics, lab services; adjusts full-year guidance
    Labcorp continues to power along as it posts strong quarterly earnings led by growth in its diagnostics and lab services and triggering the medtech to raise its full-year guidance.
    Fierce Biotech · 6h ago↗ source
  • Takeda scraps another phase 2 celiac disease therapy, narrowing pipeline to one
    Takeda has dropped another celiac disease therapy from its phase 2 pipeline, leaving the company with just one shot at treating the condition.
    Fierce Biotech · 6h ago↗ source
  • GSK pens $110M biological datasets pact with AI biotech Relation
    GSK is boosting its AI chops with a new deal worth up to $110 million with Relation.
    Fierce Biotech · 7h ago↗ source
  • Convenience Kit Correction: Argon Medical Issues Correction for Convenience Kits Containing Spectra Medical Device Lidocaine Ampules
    Argon Medical is correcting affected convenience kits by removing included Spectra Medical Devices Lidocaine Ampules.
    fda medwatch · 10h ago↗ source
  • Boston Scientific cuts guidance again after unveiling restructuring plan
    Boston Scientific is cutting its financial guidance for the second quarter in a row as it gears up for a tough six months ahead.
    Fierce Biotech · 10h ago↗ source