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  • Lilly buys another pain biotech; FDA sets decision for once-weekly PrEP pill
    Plus, news about Merck, MultiValent Biotherapies, Alvotech, enGene, Mirum, and Adaptive Biotechnologies. 💸 Eli Lilly acquires another pain biotech: The Indianapolis pharma giant has made its 11t…
    Endpoints · 1mo ago↗ source
  • UCSF spinout Kopra Bio raises $9.1M to test virus therapy in brain cancer
    Glioblastoma is notoriously good at evading the immune system, making it particularly resistant to immunotherapy, but now researchers may have found a clever workaround. Scientists at the Universi…
    Endpoints · 1mo ago↗ source
  • CMS seeks to close Medicare negotiation 'loophole'
    CMS has proposed a policy change that clarifies its stance on how products are grouped together for Medicare negotiations. Under the Inflation Reduction Act, biologics become eligible for Medicar…
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Endpoints · 1mo ago
↗ source
  • FDA plans to keep Makary priorities on trials, China, deputy says
    PHILADELPHIA – Following the recent departures of FDA Commissioner Marty Makary and both of his center directors for drugs and biologics, the Trump administration will continue pushing their priori…
    Endpoints · 1mo ago↗ source
  • Takeda fortifies orexin potential with more Phase 3 data
    With a formidable new competitor set to enter the orexin development race, Takeda is out with new data that it hopes will reinforce market-leading potential. The additional results from Takeda’s…
    Endpoints · 1mo ago↗ source
  • Elicio’s KRAS cancer vaccine fails in Phase 2, shares plummet
    Elicio Therapeutics’ pancreatic cancer vaccine failed to improve outcomes in a mid-stage study, but the company is seeking funds to move ahead to a larger Phase 3 trial anyway. Elicio reported ...
    Endpoints · 1mo ago↗ source
  • Gan & Lee's Phase 3 obesity successes; J&J touts multiple myeloma data
    Plus news about Sanofi, PharmaMar, Jazz, Rhythm Pharmaceuticals, Spyre and Zymeworks 🇨🇳 Another obesity readout from China: Gan & Lee Pharmaceuticals, a China-based insulin specialist, anno…
    Endpoints · 1mo ago↗ source
  • Neumora drug fails two more Phase 3 trials, biotech to lay off 35% of staff
    The Really Big Neuroscience Company is proving to be a Really Big Flop with each passing update. Neumora Therapeutics will discontinue its lead depression drug after it failed another two Phase 3…
    Endpoints · 1mo ago↗ source
  • Six leaders working on LGBTQ+ inclusion in biopharma
    It’s been a tough 18 months for the LGBTQ+ community. The American Civil Liberties Union tracked 530 anti-LGBTQ bills across dozens of states this year. Nearly 40% of US workers say ...
    Endpoints · 1mo ago↗ source
  • Lilly puts its stamp at #EHA26 with Jaypirca combo data in CLL, first clinical data from Ajax buyout
    Eli Lilly made a push in blood cancer at this year’s European Hematology Association meeting in Stockholm over the weekend. The drugmaker presented data for Jaypirca combined with the standard of…
    Endpoints · 1mo ago↗ source
  • HMNC Brain Health raises $50M Series B to advance two depression drugs
    HMNC Brain Health has secured $50 million in a Series B fundraise designed to support two psychiatry programs into mid-stage studies. The family-owned German drugmaker Medice led the Series B, wh…
    Endpoints · 1mo ago↗ source
  • Biopharma’s 2025 industry pay report; Parabilis sets industry record IPO; and more
    Welcome back to Endpoints Weekly! This week, we opened nominations for our eighth annual Women in Biopharma report. We’re looking to profile 20 scientists, executives, founders and other enterprisi…
    Endpoints · 1mo ago↗ source
  • Merck brings Welireg-Keytruda combo to treat kidney cancer
    Merck’s Welireg and Keytruda combination won approval as an adjuvant treatment for kidney cancer patients after surgery to remove all or part of the organ. The combination was approved Friday for…
    Endpoints · 1mo ago↗ source
  • Amgen and the FDA want two different outcomes for Tavneos. What will patients do?
    Amgen has asked the FDA to review evidence that its drug Tavneos (avacopan), which treats a rare form of vasculitis, is worth keeping on the market, as the future of the drug remains in flux. ...
    Endpoints · 1mo ago↗ source
  • Eli Lilly invests in startup Abridge for clinical trial recruitment
    Eli Lilly has invested in Abridge as the health tech startup expands into clinical trial recruitment and broadens its reach into the life sciences. The investment, made through Lilly’s venture ar…
    Endpoints · 1mo ago↗ source
  • Enliven prices $400M offering; Jazz drug Zepzelca fails confirmatory study
    Plus news about Caribou, Adial, and the Beneluxa Initiative. 💵 Enliven Therapeutics’ data and raise: The Burlingame, CA-based biotech priced a $400 million offering {$ELVN} Thursday night after…
    Endpoints · 1mo ago↗ source
  • Biopharma's pay oddities of 2025: Executive perks and eccentricities
    In combing through thousands of C-suite pay packages worth billions of dollars, it’s rare for a line item to stick out. Every once in a while, a biopharma company discloses perks that go beyond t…
    Endpoints · 1mo ago↗ source
  • WuXi AppTec sues Pentagon in challenge over inclusion on Chinese military list
    WuXi AppTec has lodged a claim against the Department of Defense following its addition to a list of companies associated with the Chinese military. Under the complaint, filed Thursday with the U…
    Endpoints · 1mo ago↗ source
  • GSK took advantage of ASCO dip to get discount on Nuvalent
    GSK’s $10.6 billion buyout of Nuvalent, announced Tuesday, was the largest in the company’s history. But did new CEO Luke Miels get a discount? At $124 a share, the price Miels paid ...
    Endpoints · 1mo ago↗ source
  • Novo's M&A leader leaves for Forbion; Perrigo CEO's 'personal conduct' issues led to resignation
    Forbion’s portfolio companies have been no stranger to M&A deals in recent years. But the Dutch investment firm now wants more of its biotechs to benefit from the industry’s ...
    Endpoints · 1mo ago↗ source
  • Sciwind has two Western partners for its obesity drug, but is open to more
    Sciwind Biosciences has already licensed its GLP-1 obesity drug ecnoglutide twice over — to Pfizer and Verdiva Bio — but it is not done yet. The Chinese biotech is seeking new partners for the ri…
    Endpoints · 1mo ago↗ source
  • The seeming inevitability of rising healthcare costs
    We’re getting our first signs of where healthcare costs are heading next year. According to a survey of actuaries at 27 health plans covering employers and individuals on the exchanges
    Endpoints · 1mo ago↗ source
  • Drugmakers are turning to logistics providers as trade disruptions linger, DHL exec says
    DHL is in discussions with multiple major drugmakers who are looking for the logistics company to either take over their sites or access its resources, the company’s supply chain business CEO Hendr…
    Endpoints · 1mo ago↗ source
  • Summit withdraws $500M offering, citing 'market conditions'
    The current biotech environment can apparently support an industry-record IPO and simultaneously hamper efforts to raise half a billion dollars. Summit Therapeutics ditched plans for a $500 milli…
    Endpoints · 1mo ago↗ source
  • Sensorion axes hearing loss program; Novartis' biomarker data in muscular dystrophy
    Plus, news about Imaavy. 👂 Sensorion selects one hearing loss program, axes another: The biotech is ending the development of SENS-501 for OTOF-related hearing loss following a “strategic revie…
    Endpoints · 1mo ago↗ source