John Carroll and Arsalan Arif at #JPM25 in San Francisco (Endpoints News) June 20, 2026 12:37 AM EDT Editor's notePublisher's note No investors. A 50/50 split everyone warned us against. How Endpoints survived its first decade — and ended up at the FT Arsalan Arif Founder and CEO John Carroll Editor & Founder We were broke when we launched Endpoints on this day ten years ago. Not startup broke, with a seed round and runway. Actually broke. No benefactors, no backup plan. Nobody to answer to because nobody had written a check. So we did something every advisor told us not to: split ownership 50/50. That type of dynamic usually ends badly for founders. But it was the only way that made sense for us. And that bond turned out to be the single most valuable asset we had. We’re still astonished, and grateful, that it held — from a bootstrapped start to a London boardroom. This was not our first rodeo. We met 20 years ago — a decade before there was an Endpoints News. Arsalan needed a real job at 26 after wrapping yet another entrepreneurial project: an amateur basketball league in Washington, DC, where games got real box scores and news write-ups. He was recruited by a friend to join the business news startup FierceMarkets as a sales rep, and figured, let’s give it a few months. His first assignment was to walk the 2006 BIO International Convention trade show floor and sell online ads to biotech brands. John was already there — a writer for FierceBiotech, a couple of years in, covering drug development with a reporter’s pen. He’d taken a long route to biopharma too. Decades in print, including a turn as an editor and publisher, then a swing at running his own thing, then freelance. We had arrived at the same company at the opposite ends of a career. We then spent years building a biotech news franchise as employees. So we knew the shape of things going in together as owners in 2016, and agreed overwhelmingly on most things: Endpoints’ mission, the quality of our writing, fiercely independent reporting, not making ourselves the story, owning distribution, having a direct relationship with readers, and being available to the job every moment you are awake. Before launch, we had a face-to-face in a midtown NYC diner. We promised to be straightforward and tell the entire truth to each other, no matter how inconvenient or insignificant. We knew the readers and the companies, and built a product serving them. There were four staffers on day one, including the two of us — almost no overhead, and nothing to pull us off the daily grind. Without an audience, we’d have been out of business inside a few months. What kept us alive was the early response from the biopharma industry — readers who showed up when we had almost nothing to offer but the work itself. Our corner of the business-media world runs on a community that reads us every single day, and you found us fast. Six months in, your reception let us put on our first real event at the JP Morgan Healthcare Conference. Seeing you face-to-face, watching the subscriber count climb hour by hour, knowing many of you firsthand — that was everything. We weren’t just beating our heads against a wall — something we both have experience in. When it worked, it really worked. At times one of us led, the other backed him, and we’d switch without scorekeeping. We were good together, and we knew it about each other. Covid was the clearest case. Biotech was the biggest story in the world, the reporting was relentless, high-stakes. Endpoints was growing into all of it at once. We were never more in sync. Our worst moments rarely happened in the room. They’d surface days later, over the phone or Zoom, once something had been sitting too long. We went to the mats a couple times, and the fights were the price of telling each other the truth. But we never held grudges. Being right about someone for so long is hard work. Neither of us could move until we both agreed what had to be done. That’s the whole reason we avoided the acrimonious splits that take founders down on every side of us, in digital media and everywhere else. By year seven, we fully agreed it was time to sell. The company has been profitable since day one — rare in this business — and neither of us comes from money, so turning what we’d built into something for our families made a hell of a lot of sense. But first we wanted the right people in place for the next stretch. We were lucky to land Drew Armstrong to run editorial, and lucky again when Ryan McRae took over the business. The brute hustle that launches a company isn’t what grows an established one, and we knew it. In 2023, the Financial Times acquired Endpoints — one of the most trusted names in journalism, and a place where Endpoints can keep doing this work for a long time. Both teams collaborate with a shared purpose. We’ve called Endpoints a work in progress for ten years, and we still do. What’s changed is that it no longer depends on the two of us agreeing before it can move. It’s a team now — a great one — and we built it to outlast the partnership that started it. That was always the point. To everyone who built this with us, the ones who showed up before any of it was obvious — thank you. Happy 10th birthday to Endpoints News! AUTHORS Arsalan Arif Founder and CEO aa@endpointsnews.com @arsalanarif Arsalan Arif on LinkedIn John Carroll Editor & Founder john@endpointsnews.com @JohnCendpts John Carroll on LinkedIn
Ten years of Endpoints News: no investors, a 50/50 split, profitable from day one. Co-founders Arsalan Arif and John Carroll on how the partnership held.
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