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Endpoints·1h ago·1 min read
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Spyre drops rheumatoid arthritis hopes for anti-TL1A drug after modest Phase 2 data

Spyre Therapeutics said Tuesday it is deprioritizing its antibody candidate for rheumatoid arthritis (RA) after the drug missed the biotech’s bar for success in a mid-stage trial. The results also put a dampener on the ...

Aug 26, 2026·read at Endpoints ↗

August 26, 2026 07:00 AM EDT R&D Spyre drops rheuma­toid arthri­tis hopes for an­ti-TL1A drug af­ter mod­est Phase 2 da­ta Ayisha Sharma News Reporter Spyre Ther­a­peu­tics said Tues­day it is de­pri­or­i­tiz­ing its an­ti­body can­di­date for rheuma­toid arthri­tis (RA) af­ter the drug missed the biotech’s bar for suc­cess in a … Sign up to read this article for free. Get free access to a limited number of articles, plus choose newsletters to get straight to your inbox. SIGN UP LOG IN BECOME A PREMIUM SUBSCRIBER

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Reporting by Endpoints.

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Rheumatoid Arthritis2Monoclonal Antibody

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