Expert Consensus Offers Guidance on Evolving Multiple Myeloma Treatment Strategies

A 2025 expert consensus presented at the Bridging the Gaps meeting highlighted how quickly multiple myeloma care is changing and gave clinicians practical advice for navigating expanding treatment options.

The panel noted that quadruplet regimens have become the preferred frontline approach, but questions remain about their use in older patients, the role of stem-cell transplant, and how long maintenance therapy should continue.

New targeted agents, including BCMA-directed drugs and CAR-T cell therapies, were reported to provide strong benefits. Experts urged early referral and careful sequencing of these modalities.

They also stressed the need for vigilant infection management to maximize patient outcomes.