House passes FDA Modernization Act 3.0 to push update of animal testing regulations

The U.S. House approved the FDA Modernization Act 3.0, a bill aimed at modernizing preclinical testing rules.

The legislation requires the FDA to revise regulations that still reference animal testing, aligning them with the 2022 FDMA 2.0 law that already allowed non-animal methods.

Lawmakers and animal-welfare groups hailed the move as a step toward a more humane and efficient drug development system, noting the agency’s 2025 roadmap that targets making animal studies an exception within three to five years.

The update could affect CROs and pharma companies by encouraging adoption of scientifically valid alternative methods, potentially shortening timelines and reducing costs.