At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.
Translational Medicine at BMS Translational medicine is a department within the Research organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments. Late-stage translational development activities build upon the early work, additionally exploring mechanisms of response/non-response, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the development of translational strategies to support the development, and maximize the potential, of BMS’s therapies post-clinical proof-of-concept, including registrations and life-cycle management. Translational disease strategies in Alzheimer’s /Neurological Diseases are derived from long term investments in developing data and deep expertise in disease biology, neuroinflammation and patient segments to assist science driven strategies for the development of the neuroscience pipeline.
Key Responsibilities:
• Develops and executes translational disease strategy in Alzheimer’s /Neurological disease areas with deep disease expertise
• Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies
• Serves as scientific expert in generating novel hypotheses for targetable biologies based on novel discoveries integrating disease work with literature and deep expertise in neuroscience
• Manages cross functional disease project teams with key interfaces in IT, bioinformatics, data sci, stats, external collaborators, contractors, other disease strategy leads and asset leads
• Maintains relationship with translational clinicians for identifying new opportunities and for gaining disease insight
• Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in neuroscience area
• Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
• Collaborate and guide bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, epigenetics, proteomics, immune profile and single cell data in order to support drug discovery and development in Alzheimer’s /Neurological Diseases.
• Manage relationships with key internal stakeholders including regulatory, clinical and commercial and scientific communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results.
• Represent the Neurology Translational Medicine function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams.
• Direct and support publications in high quality scientific, technical or medical journals.
Qualifications & Experience:
• PhD degree in a neuroscience-related field
• Minimum of 8 years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing, and interpreting multimodal biological data in an academic and/or industry setting.
• Strong background in neuroscience with focus on Alzheimer’s disease, human genetics/genomics, molecular and cellular biology is required. Knowledge in immunology is a plus.
• Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity.
• Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills.
• Prior experience with clinical trials preferred but not essential
• Strong track record of high-quality scientific publications in relevant fields
#LI-Hybrid
We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.
Compensation Overview:
Brisbane - CA - US: $184,060 - $223,036 Cambridge Crossing: $184,060 - $223,036 Princeton - NJ - US: $160,060 - $193,949 San Diego - CA - US: $176,050 - $213,334
The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.
Benefits:
Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits
How We Work Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.
Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
Candidate Rights BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
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R1605872 : Associate Director, Translational Medicine, Neuroscience