We are looking for a Senior Scientist to lead the development of LC-MS assays for protein quantitation and advanced characterisation of large biomolecules. This role involves collaborating with multidisciplinary teams and requires significant experience in advanced analytical instrumentation and sample preparation.
Senior Scientist
requirements
Minimum Qualifications: • BS in Chemistry or related field plus 5-7+ years of experience with demonstrated hands-on proficiency with advanced instrumentation, with high resolution and/or triple quadrupole LC-MS platforms OR a master’s degree with 3-5+ years of stated above experience, OR a PhD with 0-1+ years of stated above experience • Advanced experience with a variety of enzymatic and chemical methods of sample preparation for large biomolecule LC-MS, such as digestion, enrichment, depletion, and labelling or related • Experience working and communicating effectively both independently and in a team-oriented environment Preferred Qualifications: • Experience in absolute quantitation of proteins and antibodies by Multiple Reaction Monitoring (MRM) and/or Parallel Reaction Monitoring (PRM) mass spectrometry • Experience in bottom up, middle up/down, and/or top-down protein LC-MS workflows • Experience with specific workflows such as non-reduced and reduced intact mass analysis, peptide mapping, disulfide mapping, Post-Translational Modifications (PTM) characterization, glycosylation profiling, and/or free thiol analysis • Experience with bioinformatics related to the quantitation and characterization of large biomolecules such as UNIFI, BioPharma Finder, Mascot, and Scaffold • Proficiency in a variety of instrument platforms such as Thermo, Sciex, Waters, and Agilent mass spectrometers • Hands-on experience with MALDI-MS Role must be based in St. Louis, MO Pay Range for this position: $105,500 - $158,300. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!