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  1. pharmadog
  2. ›drugs
  3. ›Zoryve
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Zoryve

Marketedupdated 3mo ago
by $ARQT Arcutis Biotherapeutics, Inc.
Approved
community read0 votes

🐶 often sniffed alongside

top 2
  • tagApproval16 co-mentions · 4 sources
  • drugroflumilast16 co-mentions · 4 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 20 investigational indications.

all catalysts(0)

nothing on the calendar yet

Trials studying Zoryve

  • phase3Efficacy and Safety of Roflumilast Cream 0.3% in Subjects With Plaque Psoriasis: a Phase 3 Studycompletedn=190
  • phase3Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 71 y) (APTA-2217-07)completedn=150
  • phase3Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05)completedn=450
  • phase3A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)terminatedn=3,973
  • phase2A Study to Investigate the Biomarkers of Hemay005 in Adult Participants With Moderate to Severe COPDnot yet recruitingn=120
  • phase3Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)completedn=652
  • phase2A Study for Evaluating Safety & Efficacy of Topical Roflumilast 0.3% Foam in Hidradenitis Suppurativarecruitingn=10
  • phase3Efficacy and Safety of Roflumilast Cream in Subjects With Atopic Dermatitiscompletedn=354
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Oct 5, 2026
54 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (68)

  • Aug 19, 2042formulationUS 12453721
  • Dec 3, 2041method-of-use (U-3773)US 11707454
  • Dec 3, 2041method-of-use (U-3773)US 12329751
  • Aug 25, 2037method-of-use (U-3408)US 11129818
  • Aug 25, 2037method-of-use (U-3970)US 11129818
  • Aug 25, 2037method-of-use (U-4301)US 11129818
  • Aug 25, 2037method-of-use (U-3773)US 11129818
  • Jun 7, 2037formulationUS 10940142
  • Jun 7, 2037formulationUS 10940142
  • Jun 7, 2037formulationUS 10940142
  • Jun 7, 2037formulationUS 10940142
  • Jun 7, 2037formulationUS 11793796
  • Jun 7, 2037formulationUS 11793796
  • Jun 7, 2037formulationUS 11793796
  • Jun 7, 2037formulationUS 11793796
  • Jun 7, 2037method-of-use (U-3748)US 11819496
  • Jun 7, 2037method-of-use (U-4301)US 11819496
  • Jun 7, 2037method-of-use (U-3773)US 11819496
  • Jun 7, 2037method-of-use (U-3970)US 11819496
  • Jun 7, 2037method-of-use (U-3773)US 11992480
  • Jun 7, 2037method-of-use (U-3970)US 11992480
  • Jun 7, 2037method-of-use (U-4301)US 11992480
  • Jun 7, 2037method-of-use (U-3748)US 11992480
  • Jun 7, 2037method-of-use (U-3748)US 12005051
  • Jun 7, 2037method-of-use (U-3773)US 12005051
  • Jun 7, 2037method-of-use (U-4301)US 12005051
  • Jun 7, 2037method-of-use (U-3970)US 12005051
  • Jun 7, 2037formulationUS 12005052
  • Jun 7, 2037formulationUS 12005052
  • Jun 7, 2037formulationUS 12005052
  • Jun 7, 2037formulationUS 12005052
  • Jun 7, 2037formulationUS 12011437
  • Jun 7, 2037formulationUS 12011437
  • Jun 7, 2037formulationUS 12011437
  • Jun 7, 2037formulationUS 12011437
  • Jun 7, 2037formulationUS 12016848
  • Jun 7, 2037formulationUS 12016848
  • Jun 7, 2037formulationUS 12016848
  • Jun 7, 2037formulationUS 12016848
  • Jun 7, 2037formulationUS 12042487
  • Jun 7, 2037formulationUS 12042487
  • Jun 7, 2037formulationUS 12042487
  • Jun 7, 2037formulationUS 12042487
  • Jun 7, 2037formulationUS 12220409
  • Jun 7, 2037formulationUS 12220409
  • Jun 7, 2037formulationUS 12220409
  • Jun 7, 2037formulationUS 12220409
  • Jun 7, 2037formulationUS 12257242
  • Jun 7, 2037formulationUS 12257242
  • Jun 7, 2037formulationUS 12257242
  • Jun 7, 2037formulationUS 12257242
  • Jun 7, 2037method-of-use (U-3970)US 12310956
  • Jun 7, 2037method-of-use (U-4301)US 12310956
  • Jun 7, 2037method-of-use (U-4203)US 12310956
  • Jun 7, 2037method-of-use (U-3748)US 12310956
  • Jun 7, 2037formulationUS 12336983
  • Jun 7, 2037formulationUS 12336983
  • Jun 7, 2037formulationUS 12336983
  • Jun 7, 2037formulationUS 12336983
  • Jun 7, 2037formulationUS 12390453
  • Jun 7, 2037formulationUS 9884050
  • Jun 7, 2037formulationUS 9884050
  • Jun 7, 2037formulationUS 9884050
  • Jun 7, 2037formulationUS 9884050
  • Jun 7, 2037method-of-use (U-4301)US 9907788
  • Jun 7, 2037method-of-use (U-3970)US 9907788
  • Jun 7, 2037method-of-use (U-3408)US 9907788
  • Jun 7, 2037method-of-use (U-3773)US 9907788

FDA exclusivities (5)

  • Oct 4, 2028NSNS2.1y
  • May 22, 2028I-969Indication (3y)1.8y
  • Jul 9, 2027NSNS331d
  • Dec 15, 2026NPNP125d
  • Oct 5, 2026NPPNew Product (3y)54d

News(0)

no news has mentioned this drug yet

brand
Zoryve
generic
roflumilast
MOA
Phosphodiesterase 4 inhibitor
indication
Seborrhea
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 22m ago
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