drug · small molecule

ZENATANE

updated 3mo ago

by $RDY DR REDDYS LABORATORIES LTD🔗 ChEMBL

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Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for acne and 21 investigational indications.

targets

Retinoic acid receptor

all catalysts(0)

nothing on the calendar yet

Trials studying ZENATANE

phase2Isotretinoin vs. Doxycycline for Acneiform Rash in Patients Receiving Drugs That Target the MAPK Pathwaynot yet recruitingn=50
phase2A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastomacompletedn=59
phase2Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)terminatedn=55
phase4A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgariscompletedn=31

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brand

ZENATANE

trade names

Absorica, Absorica ld, Accutane, Amnesteem, Claravis, Isotrex

generic

ISOTRETINOIN

MOA

Retinoic acid receptor agonist

indication

INDICATIONS AND USAGE Severe Recalcitrant Nodular Acne Zenatane is indicated for the treatment of severe recalcitrant nodular acne. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. “Severe,” by definition, 2 means “many” as opposed to “few or several” nodules. Because of significant adverse effects associated with its use, Zenatane should be reserved for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Zenatane is indicated only for those patients who are not pregnant, because Zenatane can cause life threatening birth defects (see Boxed CONTRAINDICATIONS AND WARNING S ). A single course of therapy for 15 to 20 weeks has been shown to result in complete and prolonged remission of disease in many patients. 1,3,4 If a second course of therapy is needed, it should not be initiated until at least 8 weeks after completion of the first course, because experience has shown that patients may continue to improve while off Zenatane. The optimal interval before retreatment has not been defined for patients who have not completed skeletal growth (see WARNINGS: Skeletal: Bone Mineral Density, Hyperostosis, Premature Epiphyseal Closure ).

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 36m ago

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drug · small molecule

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ZENATANE

updated 3mo ago

by $RDY DR REDDYS LABORATORIES LTD🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for acne and 21 investigational indications.

targets

Retinoic acid receptor

all catalysts(0)

nothing on the calendar yet

Trials studying ZENATANE

phase2Isotretinoin vs. Doxycycline for Acneiform Rash in Patients Receiving Drugs That Target the MAPK Pathwaynot yet recruitingn=50
phase2A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastomacompletedn=59
phase2Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)terminatedn=55
phase4A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgariscompletedn=31

News(0)

no news has mentioned this drug yet

brand

ZENATANE

trade names

Absorica, Absorica ld, Accutane, Amnesteem, Claravis, Isotrex

generic

ISOTRETINOIN

MOA

Retinoic acid receptor agonist

indication

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 36m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

ZENATANE

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying ZENATANE

News(0)

Report a data issue

comments(0)

ZENATANE

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying ZENATANE

News(0)

Report a data issue

comments(0)