drug · small molecule

VOQUEZNA DUAL PAK

updated 2mo ago

by $PHAT Phathom Pharmaceuticals, Inc.🔗 ChEMBL

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Small molecule drug with a maximum clinical stage of Approval (across all indications), with 11 approved and 49 investigational indications.

targets

Bacterial penicillin-binding protein

all catalysts(0)

nothing on the calendar yet

Trials studying VOQUEZNA DUAL PAK

—Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infantsrecruitingn=1,600
phase2Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trialnot yet recruitingn=300
N/ACholine to Improve Malnutrition and Enhance Cognitionrecruitingn=1,500
phase1Drug Interaction Study on Linaprazan Glurate Capsulescompletedn=56
phase3Study to Evaluate the Efficacy and Safety of DWP14012-based Triple Therapy in Eradication of Helicobacter Pyloricompletedn=461
phase4Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis))recruitingn=120
phase3Efficacy and Safety of Rifasutenizol (TNP 2198), Rabeprazole and Amoxicillin in Participants With H. Pylori Infectioncompletedn=700
phase1A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infectioncompletedn=39

more trials →

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brand

VOQUEZNA DUAL PAK

trade names

Amix 125, Amix 250, Amix 500, Amopen, Amoram, Amoxi-inject

generic

AMOXICILLIN

MOA

12.1 Mechanism of Action Vonoprazan suppresses basal and stimulated gastric acid secretion at the secretory surface of the gastric parietal cell through inhibition of the H + , K + -ATPase enzyme system in a potassium competitive manner. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, vonoprazan has been characterized as a type of gastric proton-pump inhibitor, in that it blocks the final step of acid production. Vonoprazan does not require activation by acid. Vonoprazan may selectively concentrate in the parietal cells in both the resting and stimulated states. Vonoprazan binds to the active proton pumps in a noncovalent and reversible manner. Amoxicillin is an antibacterial drug. Clarithromycin is a macrolide antimicrobial drug [see Microbiology (12.4) ]. Acid suppression enhances the replication of H. pylori bacteria and the stability and effectiveness of antimicrobials in the treatment of H. pylori infection.

indication

1 INDICATIONS AND USAGE VOQUEZNA TRIPLE PAK, is a co-packaged product containing vonoprazan, a potassium-competitive acid blocker (PCAB), amoxicillin, a penicillin class antibacterial, and clarithromycin, a macrolide antimicrobial, indicated for the treatment of Helicobacter pylori (H. pylori) infection in adults. ( 1.1 ) VOQUEZNA DUAL PAK, is a co-packaged product containing vonoprazan, a PCAB, and amoxicillin, a penicillin class antibacterial, indicated for the treatment of H. pylori infection in adults. ( 1.1 ) To reduce the development of drug-resistant bacteria and maintain the effectiveness of VOQUEZNA TRIPLE PAK, VOQUEZNA DUAL PAK and other antibacterial drugs, VOQUEZNA TRIPLE PAK and VOQUEZNA DUAL PAK should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. ( 1.2 ) 1.1 Helicobacter pylori Infection VOQUEZNA TRIPLE PAK or VOQUEZNA DUAL PAK are indicated for the treatment of Helicobacter pylori ( H. pylori ) infection in adults [see Clinical Studies (14) ]. 1.2 Usage To reduce the development of drug-resistant bacteria and maintain the effectiveness of VOQUEZNA TRIPLE PAK, VOQUEZNA DUAL PAK and other antibacterial drugs, VOQUEZNA TRIPLE PAK and VOQUEZNA DUAL PAK should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Data sources

ClinicalTrials.gov · OpenTargets

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drug · small molecule

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VOQUEZNA DUAL PAK

updated 2mo ago

by $PHAT Phathom Pharmaceuticals, Inc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 11 approved and 49 investigational indications.

targets

Bacterial penicillin-binding protein

all catalysts(0)

nothing on the calendar yet

Trials studying VOQUEZNA DUAL PAK

—Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infantsrecruitingn=1,600
phase2Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trialnot yet recruitingn=300
N/ACholine to Improve Malnutrition and Enhance Cognitionrecruitingn=1,500
phase1Drug Interaction Study on Linaprazan Glurate Capsulescompletedn=56
phase3Study to Evaluate the Efficacy and Safety of DWP14012-based Triple Therapy in Eradication of Helicobacter Pyloricompletedn=461
phase4Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis))recruitingn=120
phase3Efficacy and Safety of Rifasutenizol (TNP 2198), Rabeprazole and Amoxicillin in Participants With H. Pylori Infectioncompletedn=700
phase1A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infectioncompletedn=39

more trials →

News(0)

no news has mentioned this drug yet

brand

VOQUEZNA DUAL PAK

trade names

Amix 125, Amix 250, Amix 500, Amopen, Amoram, Amoxi-inject

generic

AMOXICILLIN

MOA

indication

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 5m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

VOQUEZNA DUAL PAK

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying VOQUEZNA DUAL PAK

News(0)

Report a data issue

comments(0)

VOQUEZNA DUAL PAK

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying VOQUEZNA DUAL PAK

News(0)

Report a data issue

comments(0)