drug · small molecule

VIVITROL

updated 3mo ago

/ /ˌnælˈtrɛksoʊn/ /

by $ALKS Alkermes plc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 4

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 47 investigational indications.

targets

Opioid receptors; mu/kappa/delta

all catalysts(0)

nothing on the calendar yet

Trials studying VIVITROL

phase4A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)completedn=226
phase4Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)active not recruitingn=8,600
phase3Combination Gerotherapeutic Interventions for Healthspan Improvementactive not recruitingn=30
phase3Evaluate the Efficacy and Safety of Naltrexone Hydrochloride Implant in Patients With Alcohol Use Disordernot yet recruitingn=240
phase2Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent Personsnot yet recruitingn=250
phase1iSTEP-N 101b: Pharmacokinetics and Safety Study of Low- and High-Dose Naltrexone Implants vs Monthly Vivitrol in Healthy Volunteersnot yet recruitingn=33
phase4A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in Americacompletedn=500
phase2Phase II Clinical Study on the Efficacy and Safety of Naltrexone Implant in Patients With Alcohol Use Disordercompletedn=210

more trials →

News(4)

4 potential biotech M&A targets, plus a pretty sure bet from J&J
Pharma is definitely interested in making more deals. But what biotechs will come under the magnifying glass? BioSpace takes a look at companies that analysts see as near-term targets for buyouts.
biospace · 6d ago
12 ideas for tackling the U.S. alcohol epidemic
The U.S. can save lives from excess alcohol use without taking drastic measures. Here are 12 steps that can help.
stat · 28d ago
Alkermes’ incoming CEO has a plan to outplay Lilly and Takeda
Blair Jackson says the next 12 months may be the most important in Alkermes’ history, as the brain drugmaker races to join an “orexin” market that analysts see as a multibillion-dollar opportunity.
biopharma_dive · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago

brand

VIVITROL

trade names

Celupan, Trexal, Vivitrol

generic

NALTREXONE

MOA

12.1 Mechanism of Action Naltrexone is an opioid antagonist with highest affinity for the mu opioid receptor. Naltrexone has little or no opioid agonist activity.

indication

1 INDICATIONS AND USAGE Treatment with VIVITROL should be part of a comprehensive management program that includes psychosocial support. VIVITROL contains naltrexone, an opioid antagonist, and is indicated for the treatment of alcohol dependence in patients who are able to abstain from alcohol in an outpatient setting prior to initiation of treatment with VIVITROL. Patients should not be actively drinking at the time of initial VIVITROL administration ( 1.1 ). VIVITROL is indicated for the prevention of relapse to opioid dependence, following opioid detoxification ( 1.2 ). VIVITROL should be part of a comprehensive management program that includes psychosocial support ( 1 ). 1.1 Alcohol Dependence VIVITROL is indicated for the treatment of alcohol dependence in patients who are able to abstain from alcohol in an outpatient setting prior to initiation of treatment with VIVITROL. Patients should not be actively drinking at the time of initial VIVITROL administration. 1.2 Opioid Dependence VIVITROL is indicated for the prevention of relapse to opioid dependence, following opioid detoxification.

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 29m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

drug · small molecule

save

VIVITROL

updated 3mo ago

/ /ˌnælˈtrɛksoʊn/ /

by $ALKS Alkermes plc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 4

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 47 investigational indications.

targets

Opioid receptors; mu/kappa/delta

all catalysts(0)

nothing on the calendar yet

Trials studying VIVITROL

phase4A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)completedn=226
phase4Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)active not recruitingn=8,600
phase3Combination Gerotherapeutic Interventions for Healthspan Improvementactive not recruitingn=30
phase3Evaluate the Efficacy and Safety of Naltrexone Hydrochloride Implant in Patients With Alcohol Use Disordernot yet recruitingn=240
phase2Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent Personsnot yet recruitingn=250
phase1iSTEP-N 101b: Pharmacokinetics and Safety Study of Low- and High-Dose Naltrexone Implants vs Monthly Vivitrol in Healthy Volunteersnot yet recruitingn=33
phase4A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in Americacompletedn=500
phase2Phase II Clinical Study on the Efficacy and Safety of Naltrexone Implant in Patients With Alcohol Use Disordercompletedn=210

more trials →

News(4)

4 potential biotech M&A targets, plus a pretty sure bet from J&J
Pharma is definitely interested in making more deals. But what biotechs will come under the magnifying glass? BioSpace takes a look at companies that analysts see as near-term targets for buyouts.
biospace · 6d ago
12 ideas for tackling the U.S. alcohol epidemic
The U.S. can save lives from excess alcohol use without taking drastic measures. Here are 12 steps that can help.
stat · 28d ago
Alkermes’ incoming CEO has a plan to outplay Lilly and Takeda
Blair Jackson says the next 12 months may be the most important in Alkermes’ history, as the brain drugmaker races to join an “orexin” market that analysts see as a multibillion-dollar opportunity.
biopharma_dive · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago

brand

VIVITROL

trade names

Celupan, Trexal, Vivitrol

generic

NALTREXONE

MOA

12.1 Mechanism of Action Naltrexone is an opioid antagonist with highest affinity for the mu opioid receptor. Naltrexone has little or no opioid agonist activity.

indication

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 29m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

VIVITROL

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying VIVITROL

News(4)

Report a data issue

comments(0)

VIVITROL

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying VIVITROL

News(4)

Report a data issue

comments(0)