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  1. pharmadog
  2. ›drugs
  3. ›Romvimza
drug · small molecule
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vimseltinib

Marketedupdated 3mo ago
by Ono Pharmaceutical Co Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 2
  • tagApproval8 co-mentions · 2 sources
  • tagSmall Molecule4 co-mentions · 2 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for tenosynovial giant cell tumor and 2 investigational indications.

all catalysts(0)

nothing on the calendar yet

Trials studying vimseltinib

  • phase1Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participantsnot yet recruitingn=20
  • phase1Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)recruitingn=24
  • phase3Study of Vimseltinib for Tenosynovial Giant Cell Tumoractive not recruitingn=123
  • phase1Evaluate the Effect of Vimseltinib on Organic Cation Transporter 2 (OCT2)completedn=22
  • phase1Evaluate the Effect of Vimseltinib on the Pharmacokinetics of a BCRP and OATP1B1 Substratecompletedn=20
  • phase2Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumoractive not recruitingn=120
  • phase2A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)recruitingn=48

Patent cliff

source: FDA Orange Book
first barrier falls
Feb 14, 2030
~3.5 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (30)

  • Apr 30, 2045formulationUS 12509443
  • Apr 30, 2045formulationUS 12509443
  • Apr 30, 2045formulationUS 12509443
  • Dec 6, 2044formulationUS 12447149
  • Dec 6, 2044formulationUS 12447149
  • Dec 6, 2044formulationUS 12447149
  • Dec 6, 2044compositionUS 12528787
  • Dec 6, 2044compositionUS 12528787
  • Dec 6, 2044compositionUS 12528787
  • Dec 6, 2044formulationUS 12551483
  • Dec 6, 2044formulationUS 12551483
  • Dec 6, 2044formulationUS 12551483
  • Feb 3, 2040method-of-use (U-4145)US 11103507
  • Feb 3, 2040method-of-use (U-4145)US 11103507
  • Feb 3, 2040method-of-use (U-4145)US 11103507
  • Feb 3, 2040method-of-use (U-4145)US 11679110
  • Feb 3, 2040method-of-use (U-4145)US 11679110
  • Feb 3, 2040method-of-use (U-4145)US 11679110
  • Dec 23, 2039method-of-use (U-4145)US 12285430
  • Dec 23, 2039method-of-use (U-4145)US 12285430
  • Dec 23, 2039method-of-use (U-4145)US 12285430
  • Dec 23, 2039method-of-use (U-4145)US 12485120
  • Dec 23, 2039method-of-use (U-4145)US 12485120
  • Dec 23, 2039method-of-use (U-4145)US 12485120
  • Dec 23, 2039method-of-use (U-4145)US 12582655
  • Dec 23, 2039method-of-use (U-4145)US 12582655
  • Dec 23, 2039method-of-use (U-4145)US 12582655
  • Mar 14, 2034compositionUS 9181223
  • Mar 14, 2034compositionUS 9181223
  • Mar 14, 2034compositionUS 9181223

FDA exclusivities (3)

  • Feb 14, 2030NCENew Chemical Entity (5y)3.5y
  • Feb 14, 2030NCENew Chemical Entity (5y)3.5y
  • Feb 14, 2030NCENew Chemical Entity (5y)3.5y

News(0)

no news has mentioned this drug yet

brand
Romvimza
generic
vimseltinib
indication
Graft Versus Host Disease (GVHD)
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 41m ago
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