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  1. pharmadog
  2. ›drugs
  3. ›Briumvi
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ublituximab

Marketedupdated 3mo ago
by $TGTX TG THERAPEUTICS, INC.
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval20 co-mentions · 5 sources
  • drugBRIUMVI20 co-mentions · 5 sources
  • company$TGTXTG THERAPEUTICS, INC.10 co-mentions · 5 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 8 investigational indications.

all catalysts(5)

approval · 5
Dec 28, 2022
approval
$TGTX49.16-1.21%
4y ago
BRIUMVI (UBLITUXIMAB-XIIY) — FDA approval
ublituximab
→
Oct 30, 2024
approval
$TGTX49.16-1.21%
2y ago
BRIUMVI (UBLITUXIMAB-XIIY) — FDA approval
ublituximab
→
Aug 18, 2025
approval
$TGTX49.16-1.21%
12mo ago
BRIUMVI (UBLITUXIMAB-XIIY) — FDA approval
ublituximab
→
Aug 18, 2025
approval
$TGTX49.16-1.21%
12mo ago
BRIUMVI (UBLITUXIMAB-XIIY) — FDA approval
ublituximab
→
Jan 16, 2026
approval
$TGTX49.16-1.21%
7mo ago
BRIUMVI (UBLITUXIMAB-XIIY) — FDA approval
ublituximab
→

Trials studying ublituximab

  • phase2Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophreniarecruitingn=60
  • phase2A Study to Evaluate Pharmacokinetics (PK) and Safety of Subcutaneous (SC) Ublituximab Administered at Various Injection Sites and Relative Bioavailability Via Autoinjector (AI) Versus Syringe Subcutaneously in Participants With Multiple Sclerosis (MS)recruitingn=350
  • phase3Study to Assess Effects of Ublituximab in Pediatric Participants With Relapsing Forms of Multiple Sclerosisrecruitingn=240
  • phase3An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosisactive not recruitingn=1,100
  • phase3Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximabrecruitingn=800
  • phase4Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosisrecruitingn=50
  • phase2Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathyrecruitingn=30
  • phase3A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, Radiological and Clinical Effects of Subcutaneous Ublituximab in Participants With Relapsing Multiple Sclerosis (RMS)recruitingn=360
more trials →

News(0)

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brand
Briumvi
generic
ublituximab
MOA
12.1 Mechanism of Action The precise mechanism by which ublituximab-xiiy exerts its therapeutic effects in multiple sclerosis is unknown, but is presumed to involve binding to CD20, a cell surface antigen present on pre-B and mature B lymphocytes. Following cell surface binding to B lymphocytes, ublituximab-xiiy results in cell lysis through mechanisms including antibody-dependent cellular cytolysis and complement-dependent cytolysis.
indication
Relapsing Multiple Sclerosis (RMS)
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 40m ago
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