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  1. pharmadog
  2. ›drugs
  3. ›Cobenfy
drug
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(trospium chloride + xanomeline tartrate)

Marketedupdated 5mo ago
by Bristol-Myers Squibb Co
Approved
community read0 votes

indications

investigational
Schizophrenia

all catalysts(0)

nothing on the calendar yet

Patent cliff

source: FDA Orange Book
first barrier falls
Sep 26, 2029
~3.0 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (33)

  • Oct 29, 2039formulationUS 12558317
  • Oct 29, 2039formulationUS 12558317
  • Oct 29, 2039formulationUS 12558317
  • Sep 27, 2039formulationUS 10925832
  • Sep 27, 2039formulationUS 10925832
  • Sep 27, 2039formulationUS 10925832
  • Sep 27, 2039formulationUS 10933020
  • Sep 27, 2039formulationUS 10933020
  • Sep 27, 2039formulationUS 10933020
  • Sep 27, 2039method-of-use (U-3513)US 11452692
  • Sep 27, 2039method-of-use (U-3513)US 11452692
  • Sep 27, 2039method-of-use (U-3513)US 11452692
  • Sep 27, 2039method-of-use (U-3513)US 11471413
  • Sep 27, 2039method-of-use (U-3513)US 11471413
  • Sep 27, 2039method-of-use (U-3513)US 11471413
  • Sep 27, 2039formulationUS 11890378
  • Sep 27, 2039formulationUS 11890378
  • Sep 27, 2039formulationUS 11890378
  • Jul 21, 2030formulationUS 102386433.8y
  • Jul 21, 2030formulationUS 102386433.8y
  • Jul 21, 2030formulationUS 102386433.8y
  • Jul 21, 2030method-of-use (U-3513)US 102653113.8y
  • Jul 21, 2030method-of-use (U-3513)US 102653113.8y
  • Jul 21, 2030method-of-use (U-3513)US 102653113.8y
  • Jul 21, 2030method-of-use (U-3513)US 103691433.8y
  • Jul 21, 2030method-of-use (U-3513)US 103691433.8y
  • Jul 21, 2030method-of-use (U-3513)US 103691433.8y
  • Jul 21, 2030formulationUS 103691443.8y
  • Jul 21, 2030formulationUS 103691443.8y
  • Jul 21, 2030formulationUS 103691443.8y
  • Jul 21, 2030method-of-use (U-3513)US 106953393.8y
  • Jul 21, 2030method-of-use (U-3513)US 106953393.8y
  • Jul 21, 2030method-of-use (U-3513)US 106953393.8y

FDA exclusivities (3)

  • Sep 26, 2029NCENew Chemical Entity (5y)3.0y
  • Sep 26, 2029NCENew Chemical Entity (5y)3.0y
  • Sep 26, 2029NCENew Chemical Entity (5y)3.0y

News(10)

  • BMO most bullish on Merck's, bearish on BMS’ plans to contend with patent cliffs
    BMO Capital Markets is more impressed by Merck’s plans to replace lost Keytruda revenue than on Bristol Myers Squibb’s efforts to fill the expected void that will come from loss of exclusivity for…
    biospace · 2d ago
  • How J&J paved the way for Compass’ coming psychedelic drug launch
    In an interview with BioPharma Dive, Compass executives said that, should the FDA approve their treatment, they hope to capitalize on a strategy pioneered by J&J in selling the ketamine spray Sprav…
    biopharma_dive · 13d ago
  • Stripped of AstraZeneca safety net, BMS could face ‘carnage’ if high-risk clinical trial fails
    BMS is barreling toward a clinical trial readout that an H.C. Wainwright analyst believes could contribute to the return of mergers between mega-cap drugmakers.
    biospace · 1mo ago
  • BMS’ neuro renaissance was built on back of Celgene mega-merger
    Well-known for its oncology efforts and making recent headlines for a rumored mega merger with AstraZeneca, Bristol Myers Squibb is also dedicating considerable resources to neurological and psychi…
    biospace · 1mo ago
  • BMS welcomes new multiple myeloma drug as generics batter current portfolio
    The FDA approves Zenbexus just as copycat competitors depress sales of Bristol Myers Squibb’s multiple myeloma drugs Pomalyst and Revlimid, which crashed 71% and 49% year-on-year, respectively, in…
    biospace · 1mo ago
  • MapLight dims preclinical programs to make phase 3-ready schizophrenia drug shine brighter
    Despite mixed results for its experimental schizophrenia treatment last month, MapLight Therapeutics is going all-in on the asset—at the expense of its preclinical programs.
    fiercebiotech · 1mo ago
  • As BMS’ Cobenfy struggles to gain traction, MapLight knocks on the door
    Despite the recent emergence of a new drug class, schizophrenia remains one of the most challenging neuropsychiatric diseases to treat—and Cobenfy's first steps into the market indicate there is st…
    biospace · 1mo ago
  • As portfolio erodes, BMS stands to gain a lot from rumored AstraZeneca merger
    While both drugmakers face looming patent cliffs, analysts say joining forces could help Bristol Myers Squibb replenish its eroding portfolio—while the strategic case for AstraZeneca seems to be mo…
    biospace · 2mo ago
  • An AstraZeneca-Bristol Myers megamerger? Wall Street isn’t thrilled.
    In fact, the former lost tens of billions of dollars in market value following reports of a potential tie-up between the pharmaceutical giants.
    biopharma_dive · 2mo ago
  • Sanofi to ‘rebuild trust’ with Regeneron; Apnimed adds to string of ‘upsized’ biotech IPOs
    Sanofi wants to broaden the company’s productive partnership with Regeneron, its CEOs said. Elsewhere, Bristol Myers delayed two anticipated study readouts and a Shionogi-backed startup went public.
    biopharma_dive · 2mo ago
view all news mentions →
brand
Cobenfy
generic
(trospium chloride + xanomeline tartrate)
indication
Psychosis
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 15m ago
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