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  1. pharmadog
  2. ›drugs
  3. ›Trabectedin
drug · small molecule
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trabectedin

Marketedupdated 3mo ago
by $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 1
  • tagApproval28 co-mentions · 7 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 6 approved and 10 investigational indications.

all catalysts(0)

nothing on the calendar yet

Trials studying trabectedin

  • phase3A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)recruitingn=333
  • phase2Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcomarecruitingn=16
  • phase2Trial in Patients With Metastatic or Locally Advanced Leiomyosarcomarecruitingn=100
  • phase2Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamidecompletedn=50
  • phase2SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patientscompletedn=37
  • phase1Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.completedn=40
  • phase2Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcomacompletedn=29
  • phase2Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumourrecruitingn=198
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Jan 7, 2028
~1.4 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Jul 7, 2028patentUS 8895557*PED1.9y
  • Jan 7, 2028formulationUS 88955571.4y

News(0)

no news has mentioned this drug yet

brand
Trabectedin
trade names
Yondelis
generic
trabectedin
indication
Ewing Sarcoma
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 26m ago
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