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  1. pharmadog
  2. ›drugs
  3. ›tominersen
drug · oligonucleotide
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tominersen

Phase 2updated 3mo ago
by F. Hoffmann-La Roche Ltd🔗 ChEMBL
Phase 2
community read0 votes

Oligonucleotide drug with a maximum clinical stage of Phase 3 (across all indications), with 5 investigational indications.

targets

Huntingtin mRNA

all catalysts(0)

nothing on the calendar yet

Trials studying tominersen

  • phase2GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Diseaseactive not recruitingn=301

News(3)

  • Roche drops TCE for lupus, but hasn’t given up on autoimmune cell therapies
    Roche may have scrapped work on a T-cell engager being evaluated for lupus, but the company’s head of pharma told Fierce that still has a strategy for developing cell therapies for autoimmune disea…
    fiercebiotech · 25d ago
  • Roche scraps two Ionis-partnered Huntington’s drugs
    The Swiss pharmaceutical giant told patient groups tominersen didn't delay disease progression in one trial, while a study of a second drug was scrapped because of a safety signal in animal testing.
    biopharma_dive · 1mo ago
  • Roche ends work on tominersen after decade of trials, as well as early-stage Huntington’s asset
    After more than a decade of work and plenty of ups and downs, Roche has dropped its Huntington’s disease drug tominersen. The decision comes after tominersen did no better than placebo in a Phase 2…
    endpoints · 1mo ago
generic
tominersen
MOA
Huntingtin mRNA antisense inhibitor
indication
Huntington Disease
phase
phase_2
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 32m ago
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