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  1. pharmadog
  2. ›drugs
  3. ›Tivdak
drug · antibody drug conjugate
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tisotumab vedotin

Marketedupdated 3mo ago
by Genmab AS🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 2
  • drugTIVDAK16 co-mentions · 4 sources
  • tagApproval16 co-mentions · 4 sources

Antibody drug conjugate drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 3 investigational indications.

indications

investigational
NSCLC

targets

Tissue factorTubulin

all catalysts(4)

approval · 4
Sep 20, 2021
approval
5y ago
TIVDAK (TISOTUMAB VEDOTIN-TFTV) — FDA approval
tisotumab vedotin
→
Jul 26, 2023
approval
3y ago
TIVDAK (TISOTUMAB VEDOTIN-TFTV) — FDA approval
tisotumab vedotin
→
Apr 29, 2024
approval
2y ago
TIVDAK (TISOTUMAB VEDOTIN-TFTV) — FDA approval
tisotumab vedotin
→
Nov 12, 2025
approval
9mo ago
TIVDAK (TISOTUMAB VEDOTIN-TFTV) — FDA approval
tisotumab vedotin
→

Trials studying tisotumab vedotin

  • phase3A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)recruitingn=686
  • phase2Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumorsactive not recruitingn=350
  • phase4Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancerrecruitingn=100
  • phase2Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancerterminatedn=214
  • phase3Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancercompletedn=502
  • phase1To Evaluate Pharmacokinetics of Tisotumab Vedotin in Chinese Subjects With Metastatic or Recurrent Solid Malignanciescompletedn=19
  • phase2A Trial of Tisotumab Vedotin in Cervical Cancercompletedn=102

News(1)

  • Pfizer expands multibillion-dollar cost-cutting plan
    Hatched three years ago, the restructuring is now expected to deliver $1 billion in new cost reductions and save Pfizer another $1.5 billion by streamlining drug production.
    biopharma_dive · 10d ago
brand
Tivdak
trade names
Tivdak
generic
tisotumab vedotin-tftv
MOA
Coagulation factor III binding agent; Tubulin inhibitor
indication
Bladder Cancer
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 48m ago
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