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  1. pharmadog
  2. ›drugs
  3. ›tebapivat
drug · small molecule
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tebapivat

Phase 2updated 3mo ago
by $AGIO AGIOS PHARMACEUTICALS, INC.🔗 ChEMBL
Phase 2
community read0 votes

Small molecule drug with a maximum clinical stage of Phase 2, with 1 investigational indication.

indications

indications
Sickle Cell Disease

all catalysts(0)

nothing on the calendar yet

Trials studying tebapivat

  • phase2A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)active not recruitingn=87
  • phase2A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)active not recruitingn=59
  • phase1A Study to Determine How Tebapivat is Absorbed, Broken Down, and Removed From the Body and the Extent to Which Tebapivat is Made Available in the Body in Healthy Participantscompletedn=8

News(8)

  • Biotechs bring big launches and pharma rivalries into Q2 earnings period
    With the second quarter earnings period underway, BioSpace examines five biotechs with meaningful catalysts that analysts and investors are watching.
    biospace · 22d ago
  • Agios scraps sickle cell drug
    The study failure costs Agios a chance to one-up Novo Nordisk and represents yet another setback in a disease that’s frustrated drugmakers of late.
    biopharma_dive · 1mo ago
  • Agios’ second shot at sickle cell disease falls short
    Agios said it is dropping a next-generation sickle cell disease drug after lackluster results from a mid-stage trial. The drug, known as tebapivat, represented Agios’ second shot at the disease, an…
    endpoints · 1mo ago
  • Agios axes next-gen sickle cell candidate after it fails to best Novo’s asset
    Agios Pharmaceuticals’ sickle cell disease candidate didn’t prove any better than Novo Nordisk’s investigational PK activator or the biopharma’s own asset that is currently under FDA review for the…
    biospace · 1mo ago
  • STAT+: Anthropic deepens work with rare disease drugs
    Novo Nordisk sues Eli Lilly over GLP-1s, Medicare pricing plans, and more biotech news from The Readout
    stat · 1mo ago
  • Agios says adios to sickle cell program over lackluster phase 2 data
    A phase 2 study of Agios Pharmaceuticals’ next-generation pyruvate kinase activator has failed to support continued development in sickle cell disease, leading the company to ax an indication for t…
    fiercebiotech · 1mo ago
  • Agios ends development of tebapivat in low-risk MDS following subpar results
    Agios Pharmaceuticals has said it will stop developing its rare blood disorder drug for certain patients with myelodysplastic syndromes (MDS) due to disappointing Phase 2b data. The biotech’s pyruv…
    endpoints · 2mo ago
  • Allogene CEO to step down; Agios drug fails key test
    David Chang will leave his post after an eight-year run at the cell therapy maker. Elsewhere, a next-generation blood disease drug stumbled and an acquisition yielded an FDA approval for AbbVie.
    biopharma_dive · 2mo ago
generic
tebapivat
indication
Sickle Cell Disease
phase
phase_2
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 40m ago
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