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  1. pharmadog
  2. ›drugs
  3. ›Talvey
drug · antibody
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talquetamab

Marketedupdated 5mo ago
by $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval32 co-mentions · 8 sources
  • drugTALVEY32 co-mentions · 8 sources
  • companyJanssen Biotech Inc16 co-mentions · 8 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for multiple myeloma and neoplasm.

targets

G-protein coupled receptor family C group 5 member DT cell surface glycoprotein CD3

all catalysts(8)

approval · 8
Aug 9, 2023
approval
3y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Nov 16, 2023
approval
3y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Feb 20, 2024
approval
3y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Jul 2, 2024
approval
2y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Dec 2, 2024
approval
2y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Aug 19, 2025
approval
1y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Oct 2, 2025
approval
1y ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Mar 5, 2026
approval
7mo ago
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
view all 8 catalysts →

Trials studying talquetamab

  • phase3A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatmentactive not recruitingn=864
  • phase2A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Eventsrecruitingn=210
  • phase3A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomideactive not recruitingn=838
  • phase1A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myelomaactive not recruitingn=166
  • phase2A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myelomaactive not recruitingn=43
  • phase2Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)recruitingn=50
  • phase1A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myelomaactive not recruitingn=74
  • phase2Outpatient Administration of Teclistamab or Talquetamab for Multiple Myelomarecruitingn=100

News(8)

  • Novartis wagers almost $8B on a Chinese biotech’s RNA drugs
    In exchange for a $575 million payment up front, Abogen Biosciences will furnish Novartis with access to its RNA technology, including an option to license its lead program ABO-2203.
    biopharma_dive · 2d ago
  • GSK bags Chimagen’s trispecific T cell engager in deal worth up to $750M
    After inking a T cell engager pact with Chimagen Biosciences a few years ago, GSK is back for more, this time acquiring a multiple myeloma program from the antibody specialist.
    biospace · 19d ago
  • GSK doubles down on Chimagen with $750M multiple myeloma wager
    GSK has bet up to $750 million on a Chimagen Biosciences trispecific T-cell engager, positioning the Big Pharma to start phase 1 development of the multiple myeloma drug candidate next year. The de…
    fiercebiotech · 19d ago
  • Bristol Myers’ pivotal CAR-T multiple myeloma trial hits primary endpoint
    A pivotal trial of Bristol Myers Squibb’s GPRC5D-directed CAR-T cell therapy has hit its primary endpoint, furthering the drugmaker’s efforts to challenge Johnson & Johnson for the post-BCMA multip…
    fiercebiotech · 26d ago
  • Legend Biotech CEO abruptly steps down without permanent replacement
    In a sudden leadership shift, Legend Biotech announced that its CEO, Ying Huang, Ph.D., resigned on Friday, with no permanent replacement yet named.
    fiercebiotech · 2mo ago
  • Novo escalates legal fight with Lilly; J&J reinforces ‘dominance’ in multiple myeloma
    Novo is seeking an injunction that would halt allegedly “misleading” obesity drug ads. Elsewhere, the FDA began reviewing a highly anticipated medicine and a veteran investor landed at an AI startup.
    biopharma_dive · 2mo ago
  • J&J multiple myeloma drug gains edge in earlier stage disease
    The latest results studying Talvey in combination with Darzalex Faspro support J&J’s efforts to expand the immunotherapy's use.
    biopharma_dive · 3mo ago
  • Dr Silbermann on Clinical Trial Design Considerations in Multiple Myeloma
    Rebecca Silbermann, MD, MMS, outlines key trial design considerations in multiple myeloma, including supportive care measures and end point selection.
    onclive · 4mo ago
brand
Talvey
trade names
Talvey
generic
talquetamab-tgvs
MOA
G-protein coupled receptor family C group 5 member D binding agent; T cell surface glycoprotein CD3 binding agent
indication
Refractory Multiple Myeloma
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 56m ago
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