drug · antibody
talquetamab
Marketedupdated 5mo agoby $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approvedcommunity read0 votes
🐶 often sniffed alongside
top 3Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for multiple myeloma and neoplasm.
targets
G-protein coupled receptor family C group 5 member DT cell surface glycoprotein CD3
all catalysts(8)
approval · 8
Aug 9, 2023
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
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Nov 16, 2023
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
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Feb 20, 2024
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
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Jul 2, 2024
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
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Dec 2, 2024
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
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Aug 19, 2025
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Oct 2, 2025
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Mar 5, 2026
approval
TALVEY (TALQUETAMAB-TGVS) — FDA approval
talquetamab
→
Trials studying talquetamab
- phase3A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
- phase2A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events
- phase3A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
- phase1A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
- phase2A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma
- phase2Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)
- phase1A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma
- phase2Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma
News(8)
- Novartis wagers almost $8B on a Chinese biotech’s RNA drugsIn exchange for a $575 million payment up front, Abogen Biosciences will furnish Novartis with access to its RNA technology, including an option to license its lead program ABO-2203.biopharma_dive · 2d ago
- GSK bags Chimagen’s trispecific T cell engager in deal worth up to $750MAfter inking a T cell engager pact with Chimagen Biosciences a few years ago, GSK is back for more, this time acquiring a multiple myeloma program from the antibody specialist.biospace · 19d ago
- GSK doubles down on Chimagen with $750M multiple myeloma wagerGSK has bet up to $750 million on a Chimagen Biosciences trispecific T-cell engager, positioning the Big Pharma to start phase 1 development of the multiple myeloma drug candidate next year. The de…fiercebiotech · 19d ago
- Bristol Myers’ pivotal CAR-T multiple myeloma trial hits primary endpointA pivotal trial of Bristol Myers Squibb’s GPRC5D-directed CAR-T cell therapy has hit its primary endpoint, furthering the drugmaker’s efforts to challenge Johnson & Johnson for the post-BCMA multip…fiercebiotech · 26d ago
- Legend Biotech CEO abruptly steps down without permanent replacementIn a sudden leadership shift, Legend Biotech announced that its CEO, Ying Huang, Ph.D., resigned on Friday, with no permanent replacement yet named.fiercebiotech · 2mo ago
- Novo escalates legal fight with Lilly; J&J reinforces ‘dominance’ in multiple myelomaNovo is seeking an injunction that would halt allegedly “misleading” obesity drug ads. Elsewhere, the FDA began reviewing a highly anticipated medicine and a veteran investor landed at an AI startup.biopharma_dive · 2mo ago
- J&J multiple myeloma drug gains edge in earlier stage diseaseThe latest results studying Talvey in combination with Darzalex Faspro support J&J’s efforts to expand the immunotherapy's use.biopharma_dive · 3mo ago
- Dr Silbermann on Clinical Trial Design Considerations in Multiple MyelomaRebecca Silbermann, MD, MMS, outlines key trial design considerations in multiple myeloma, including supportive care measures and end point selection.onclive · 4mo ago
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