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  1. pharmadog
  2. ›drugs
  3. ›SYMDEKO (COPACKAGED)
drug · small molecule
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SYMDEKO (COPACKAGED)

updated 3mo ago
/ EYE-və-KAF-tər /
by $VERX Vertex, Inc.🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval286 co-mentions · 91 sources
  • drugORKAMBI253 co-mentions · 91 sources
  • drugKALYDECO233 co-mentions · 91 sources
  • drugivacaftor233 co-mentions · 91 sources
  • tagSmall Molecule143 co-mentions · 91 sources
  • drugTRIKAFTA (COPACKAGED)38 co-mentions · 19 sources
  • drug(ivacaftor + lumacaftor)20 co-mentions · 20 sources
  • drug(elexacaftor + ivacaftor + tezacaftor) + ivacaftor19 co-mentions · 19 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 8 investigational indications.

targets

Cystic fibrosis transmembrane conductance regulator

all catalysts(0)

nothing on the calendar yet

Trials studying SYMDEKO (COPACKAGED)

  • phase1Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosisrecruitingn=255
  • phase2A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CFrecruitingn=192
  • phase2Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansioncompletedn=40
  • phase2The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftorcompletedn=40
  • phase1Bioequivalence and Food Effect Bioavailability Study of Lumacaftor Film-Coated Tabletscompletedn=39
  • phase2A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD in Cystic Fibrosis Patients With at Least 1 G542X Allelecompletedn=17
  • phase2Gut Imaging for Function & Transit in Cystic Fibrosis Study 2completedn=12

News(0)

no news has mentioned this drug yet

brand
SYMDEKO (COPACKAGED)
trade names
Ivacaftor component of orkambi, Ivacaftor component of symkevi, Ivacaftor component of trikafta, Kalydeco
generic
IVACAFTOR
MOA
Cystic fibrosis transmembrane conductance regulator positive modulator; Cystic fibrosis transmembrane conductance regulator activator
indication
primary ciliary dyskinesia
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 1m ago
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