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  1. pharmadog
  2. ›drugs
  3. ›Inpefa
drug · small molecule
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sotagliflozin

Marketedupdated 2mo ago
by $LXRX LEXICON PHARMACEUTICALS, INC.🔗 ChEMBL
Approved
community read0 votes

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 6 approved and 6 investigational indications.

targets

Sodium/glucose cotransporter 1Sodium/glucose cotransporter 2

all catalysts(0)

nothing on the calendar yet

Trials studying sotagliflozin

  • phase2Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetesrecruitingn=320
  • phase3Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Diseaserecruitingn=150
  • phase3A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathyrecruitingn=500
  • phase3CKM For Safe Use of SGLT2i in Type 1 Diabetesnot yet recruitingn=52
  • EP1Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet Drugsrecruitingn=20
  • phase2Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetesrecruitingn=24

Patent cliff

source: FDA Orange Book
first barrier falls
May 4, 2028
~1.8 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (6)

  • Oct 7, 2030compositionUS 82171564.2y
  • Oct 7, 2030compositionUS 82171564.2y
  • May 29, 2028compositionUS 84764131.8y
  • May 29, 2028compositionUS 84764131.8y
  • May 4, 2028compositionUS 77815771.8y
  • May 4, 2028compositionUS 77815771.8y

FDA exclusivities (2)

  • May 26, 2028NCENew Chemical Entity (5y)1.8y
  • May 26, 2028NCENew Chemical Entity (5y)1.8y

News(0)

no news has mentioned this drug yet

brand
Inpefa
trade names
Inpefa, Zynquista
generic
sotagliflozin
MOA
Sodium/glucose cotransporter 1 inhibitor; Sodium/glucose cotransporter 2 inhibitor
indication
Hypertrophic Cardiomyopathy
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 3h ago
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