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  1. pharmadog
  2. ›drugs
  3. ›SELEXIPAG
drug · small molecule
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SELEXIPAG

Marketedupdated 3mo ago
by $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval2 co-mentions · 1 sources
  • companyRK Pharma Inc1 co-mentions · 1 sources
  • tagSmall Molecule1 co-mentions · 1 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for 4 indications.

targets

Prostacyclin receptor

all catalysts(1)

approval · 1
Apr 16, 2026
approval
4mo ago
SELEXIPAG — FDA approval
SELEXIPAG
→

Trials studying SELEXIPAG

  • phase3A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertensionactive not recruitingn=138
  • phase2Effects of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosiscompletedn=74
  • phase2A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertensionactive not recruitingn=63
  • phase3A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Optionrecruitingn=280
  • —Individual Patient Expanded Access IND for Selexipag (Uptravi) in Participants With Non-healing Wound, Buerger's Diseaseapproved for marketing
  • phase3Selexipag (ACT-293987) in Pulmonary Arterial Hypertensioncompletedn=1,156
  • phase3Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertensioncompletedn=20
  • phase1A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjectscompletedn=22
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Oct 31, 2026
77 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (104)

  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10821108*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Jun 1, 2037patentUS 10828298*PED
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10821108
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Dec 1, 2036formulationUS 10828298
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Feb 1, 2031patentUS 8791122*PED4.5y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Dec 25, 2030patentUS 9284280*PED4.4y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Aug 1, 2030compositionUS 87911224.0y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Jun 25, 2030method-of-use (U-1831)US 92842803.9y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Feb 12, 2030patentUS 9173881*PED3.5y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Aug 12, 2029method-of-use (U-1798)US 91738813.0y
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Apr 30, 2027patentUS 7205302*PED258d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d
  • Oct 31, 2026compositionUS 720530277d

News(1)

  • After missed endpoint, Gossamer and Chiesi pull the plug on PAH drug collaboration
    After signing a deal worth up to $486 million with Italian biopharma Chiesi to develop its pulmonary arterial hypertension (PAH) candidate seralutinib in 2024, Gossamer Bio has ended the collaborat…
    fiercebiotech · 18d ago
brand
SELEXIPAG
trade names
Uptravi
generic
SELEXIPAG
MOA
Prostanoid IP receptor agonist
indication
Pulmonary Arterial Hypertension
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 49m ago
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