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  1. pharmadog
  2. ›drugs
  3. ›Trodelvy
drug · antibody drug conjugate
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sacituzumab govitecan

pre_registrationupdated 3mo ago
by $GILD GILEAD SCIENCES, INC.🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 4
  • tagOncology4 co-mentions · 1 sources
  • companyNational Cancer Institute US1 co-mentions · 1 sources
  • tagPulmonology1 co-mentions · 1 sources
  • tagNSCLC1 co-mentions · 1 sources

Antibody drug conjugate drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 15 investigational indications.

targets

Tumor-associated calcium signal transducer 2DNA topoisomerase 1

all catalysts(1)

phase 1 2 initiation · 1
Apr 27, 2026
phase 1 2 initiation
4mo ago
National Cancer Institute US — sacituzumab govitecan (Phase I/II Trial Initiation)
sacituzumab govitecan
→

Trials studying sacituzumab govitecan

  • phase3Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)active not recruitingn=640
  • phase2A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancerrecruitingn=20
  • phase2Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancersrecruitingn=30
  • phase2A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancerrecruitingn=1,132
  • phase2Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.active not recruitingn=75
  • phase3NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancernot yet recruitingn=765
  • phase3Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)active not recruitingn=603
  • phase1Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Canceractive not recruitingn=18
more trials →

News(10)

  • Merck, Gilead report mixed outcomes in key lung cancer, HIV studies
    Trodelvy's latest setback carries implications for a newly important Merck drug, while the success of a once-weekly HIV tablet could boost Gilead's main business.
    biopharma_dive · 2mo ago
  • Gilead and Merck’s latest trial success and flop
    AstraZeneca's GLP-1 pill, GSK's $10.6B cancer startup acquisition, and more biotech news from The Readout
    stat · 2mo ago
  • Trodelvy misses in lung cancer, but Gilead and Merck have an HIV success
    Gilead Sciences and Merck have reported a hit and a miss for their Phase 3 HIV and lung cancer programs, respectively, but investors were largely braced for impact, according to Wall Street. The pa…
    endpoints · 2mo ago
  • At ASCO, Merck makes case for a ‘cornerstone’ cancer drug
    Study results accrued so far are giving Merck greater conviction that the therapy, licensed from a China-based biotech, was worth placing into a sprawling Phase 3 program.
    biopharma_dive · 2mo ago
  • Merck ADC, licensed from China, hits mark in first big global trial
    The endometrial cancer trial is the first of 17 late-stage studies Merck is running for a therapy that’s important to its ambitions of hitting $70 billion in annual sales next decade.
    biopharma_dive · 2mo ago
  • Honesty and Humor Provide Hope in Breast Cancer Survivorship: With Sara Nunnery, MD, MSCI; and Annie Bond
    Dr Nunnery and Annie Bond discuss breast cancer survivorship and patient advocacy.
    onclive · 3mo ago
  • GU Cancer Experts Highlight Top Abstracts to Watch During ASCO 2026
    We spoke with leading voices in GU oncology to see which presentations they are most looking forward to during the 2026 ASCO Annual Meeting.
    onclive · 3mo ago
  • Dr Silbermann on Clinical Trial Design Considerations in Multiple Myeloma
    Rebecca Silbermann, MD, MMS, outlines key trial design considerations in multiple myeloma, including supportive care measures and end point selection.
    onclive · 3mo ago
  • MimiVax and Roswell Park Open Phase 2 Trial of SurVaxM for Patients with Metastatic Neuroendocrine Tumors
    Roswell Park Comprehensive Cancer Center launched a phase 2 trial evaluating SurVaxM plus temozolomide in progressing neuroendocrine tumors.
    onclive · 3mo ago
  • Dr Randall on the Rationale for Investigating CSF-1R Inhibition in TGCT
    R. Lor Randall, MD, FACS discusses safety and efficacy data from the MANEUVER trial, which evaluated pimicotinib in TGCT.
    onclive · 3mo ago
view all news mentions →
brand
Trodelvy
trade names
Trodelvy
generic
sacituzumab govitecan
MOA
Tumor-associated calcium signal transducer 2 binding agent; DNA topoisomerase I inhibitor
indication
Triple-Negative Breast Cancer (TNBC)
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 6m ago
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