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  1. pharmadog
  2. ›drugs
  3. ›Trodelvy
drug · antibody drug conjugate
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sacituzumab govitecan

pre_registrationupdated 5mo ago
by $GILD GILEAD SCIENCES, INC.🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 4
  • tagOncology4 co-mentions · 1 sources
  • companyNational Cancer Institute US1 co-mentions · 1 sources
  • tagPulmonology1 co-mentions · 1 sources
  • tagNSCLC1 co-mentions · 1 sources

Antibody drug conjugate drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 15 investigational indications.

targets

Tumor-associated calcium signal transducer 2DNA topoisomerase 1

all catalysts(1)

phase 1 2 initiation · 1
Apr 27, 2026
phase 1 2 initiation
6mo ago
National Cancer Institute US — sacituzumab govitecan (Phase I/II Trial Initiation)
sacituzumab govitecan
→

Trials studying sacituzumab govitecan

  • phase2Study of AVZO-021 in Patients With Advanced Solid Tumorsrecruitingn=430
  • phase2A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)active not recruitingn=256
  • phase2A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancerrecruitingn=1,132
  • phase1Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumorsrecruitingn=278
  • phase3Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)active not recruitingn=640
  • phase2A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancerrecruitingn=20
  • phase2Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancersrecruitingn=30
  • phase2Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.active not recruitingn=75

News(10)

  • WCLC ‘26: A new ‘ADC era,’ China questions and AstraZeneca’s spotlight
    The year’s biggest meeting on lung cancer research featured data suggesting a new treatment standard for an aggressive tumor as well as debate about the reliability of results from China-run studies.
    biopharma_dive · 23d ago
  • BioNTech sets survival standard in hard-to-treat cancer ahead of pivotal readout
    BioNTech has linked gotistobart to a median overall survival of 18.5 months in relapsed lung cancer patients, adding to evidence that the anti-CTLA-4 antibody is better than the standard of care.
    fiercebiotech · 28d ago
  • CEO O’Day tells Fierce how Gilead’s cancer, inflammation expansion has reached ‘critical mass’
    Following a steady stream of acquisitions that culminated in three biotech buyouts earlier this year, Gilead has now reached “critical mass” in its efforts to diversify into oncology and inflammati…
    fiercebiotech · 29d ago
  • Genentech doubles down on ADC-resistant cancers with $1B DualityBio pact
    Roche’s Genentech is paying DualityBio $45 million upfront for rights to antibody-drug conjugates (ADCs) designed for the growing pool of patients who progress after treatment with the modality. Th…
    fiercebiotech · 1mo ago
  • Merck, Gilead report mixed outcomes in key lung cancer, HIV studies
    Trodelvy's latest setback carries implications for a newly important Merck drug, while the success of a once-weekly HIV tablet could boost Gilead's main business.
    biopharma_dive · 4mo ago
  • Gilead and Merck’s latest trial success and flop
    AstraZeneca's GLP-1 pill, GSK's $10.6B cancer startup acquisition, and more biotech news from The Readout
    stat · 4mo ago
  • Trodelvy misses in lung cancer, but Gilead and Merck have an HIV success
    Gilead Sciences and Merck have reported a hit and a miss for their Phase 3 HIV and lung cancer programs, respectively, but investors were largely braced for impact, according to Wall Street. The pa…
    endpoints · 4mo ago
  • At ASCO, Merck makes case for a ‘cornerstone’ cancer drug
    Study results accrued so far are giving Merck greater conviction that the therapy, licensed from a China-based biotech, was worth placing into a sprawling Phase 3 program.
    biopharma_dive · 4mo ago
  • Merck ADC, licensed from China, hits mark in first big global trial
    The endometrial cancer trial is the first of 17 late-stage studies Merck is running for a therapy that’s important to its ambitions of hitting $70 billion in annual sales next decade.
    biopharma_dive · 4mo ago
  • Honesty and Humor Provide Hope in Breast Cancer Survivorship: With Sara Nunnery, MD, MSCI; and Annie Bond
    Dr Nunnery and Annie Bond discuss breast cancer survivorship and patient advocacy.
    onclive · 4mo ago
view all news mentions →
brand
Trodelvy
trade names
Trodelvy
generic
sacituzumab govitecan
MOA
Tumor-associated calcium signal transducer 2 binding agent; DNA topoisomerase I inhibitor
indication
Triple-Negative Breast Cancer (TNBC)
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 1h ago
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