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  1. pharmadog
  2. ›drugs
  3. ›Skyrizi
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risankizumab

Marketedupdated 3mo ago
by $ABBV AbbVie Inc.
Approved
annual revenue · 2024–2024peak $11.7B
2024: $11.7B2024$11.7B
community read0 votes

🐶 often sniffed alongside

top 3
  • drugSKYRIZI92 co-mentions · 23 sources
  • tagApproval92 co-mentions · 23 sources
  • company$ABBVAbbVie Inc.46 co-mentions · 23 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 6 investigational indications.

indications

investigational
IBD (Crohn's + UC)

all catalysts(23)

approval · 23
Apr 23, 2019
approval
$ABBV249.50+0.61%
7y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 20, 2020
approval
$ABBV249.50+0.61%
6y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Apr 26, 2021
approval
$ABBV249.50+0.61%
5y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Apr 26, 2021
approval
$ABBV249.50+0.61%
5y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jan 21, 2022
approval
$ABBV249.50+0.61%
5y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jun 16, 2022
approval
$ABBV249.50+0.61%
4y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jun 16, 2022
approval
$ABBV249.50+0.61%
4y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Sep 23, 2022
approval
$ABBV249.50+0.61%
4y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Sep 23, 2022
approval
$ABBV249.50+0.61%
4y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jan 3, 2024
approval
$ABBV249.50+0.61%
3y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jan 3, 2024
approval
$ABBV249.50+0.61%
3y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 4, 2024
approval
$ABBV249.50+0.61%
2y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 4, 2024
approval
$ABBV249.50+0.61%
2y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jun 18, 2024
approval
$ABBV249.50+0.61%
2y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Jun 18, 2024
approval
$ABBV249.50+0.61%
2y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
May 7, 2025
approval
$ABBV249.50+0.61%
1y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
May 7, 2025
approval
$ABBV249.50+0.61%
1y ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Sep 3, 2025
approval
$ABBV249.50+0.61%
11mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Sep 3, 2025
approval
$ABBV249.50+0.61%
11mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 6, 2026
approval
$ABBV249.50+0.61%
5mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 6, 2026
approval
$ABBV249.50+0.61%
5mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 18, 2026
approval
$ABBV249.50+0.61%
5mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
Mar 18, 2026
approval
$ABBV249.50+0.61%
5mo ago
SKYRIZI (RISANKIZUMAB-RZAA) — FDA approval
risankizumab
→
view all 23 catalysts →

Trials studying risankizumab

  • phase3A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's Diseaseactive not recruitingn=1,336
  • phase3A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumabactive not recruitingn=573
  • phase3A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitisrecruitingn=120
  • phase3A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumabrecruitingn=40
  • phase3A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Diseaserecruitingn=530
  • phase2Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Diseaserecruitingn=540
  • phase3A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Diseaserecruitingn=110
  • phase3Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Responserecruitingn=600
more trials →

News(10)

  • MoonLake’s nanobody boosts all clinical endpoints in phase 3 psoriatic arthritis trial
    MoonLake Immunotherapeutics announced positive phase 3 data for patients with psoriatic arthritis treated with its lead nanobody candidate, sonelokimab.
    fiercebiotech · 1d ago
  • AbbVie touts strong momentum for Skyrizi despite rising competition
    If AbbVie executives are bothered by growing threats to their immunology powerhouse, they aren't letting on. Earlier this year, analysts were wondering how the company’s blockbuster Skyrizi might f…
    endpoints · 11d ago
  • AbbVie shares pressured as Q2 I&I beat falls below investor expectations
    AbbVie investors’ sky-high expectations led to a 4% share decline on Friday as the company reported more modest consensus beats than expected.
    biospace · 11d ago
  • Chutes & Ladders—Legend CEO departs without successor in place
    Legend Biotech CEO Ying Huang, Ph.D., has left the company suddenly, without a predecessor in place. Huang was elevated from CFO to CEO in 2020 after a Chinese customs investigation was opened on f…
    fiercebiotech · 12d ago
  • ‘Reverse mergers are increasingly popular’: Caldera hops on Synlogic’s Nasdaq listing
    Caldera Therapeutics has struck a reverse merger with the publicly traded Synlogic and inked a $278 million financing deal, continuing the meteoric rise of the inflammatory bowel disease startup.
    fiercebiotech · 13d ago
  • Sarepta names former AbbVie R&D exec Michael Severino as next CEO
    After leaving Tessera Therapeutics earlier this month, Michael Severino will take over Sarepta Therapeutics as the biotech awaits two key regulatory decisions in Duchenne muscular dystrophy.
    biospace · 15d ago
  • Fresh off buyout, Akero execs reunite to advance long-acting psoriasis pill
    Set to go public via a reverse merger, Avere has licensed from a prolific Chinese drugmaker rights to a potential threat to medicines like Skyrizi and Icotyde.
    biopharma_dive · 28d ago
  • Takeda’s $4B TYK2 drug tops Bristol Myers’ Sotyktu in head-to-head test
    The results support Takeda’s long-held belief in zasocitinib’s superiority and could help it gain a commercial advantage over Bristol’s therapy.
    biopharma_dive · 2mo ago
  • AbbVie faces questions about Skyrizi competition from J&J
    Threats to AbbVie's immunology dominance took center stage on the company's first-quarter earnings call Wednesday morning, as analysts pressed executives on their defense strategy. The heart of the…
    endpoints · 3mo ago
  • Oruka surges as long-acting psoriasis drug shows early promise
    A therapy that works similarly to AbbVie’s blockbuster Skyrizi appeared more potent in a mid-stage trial and has the potential to be dosed less frequently.
    biopharma_dive · 3mo ago
view all news mentions →
brand
Skyrizi
generic
risankizumab-rzaa
MOA
12.1 Mechanism of Action Risankizumab-rzaa is a humanized IgG1 monoclonal antibody that selectively binds to the p19 subunit of human IL-23 cytokine and inhibits its interaction with the IL-23 receptor. IL-23 is a naturally occurring cytokine that is involved in inflammatory and immune responses. Risankizumab-rzaa inhibits the release of pro-inflammatory cytokines and chemokines.
indication
Psoriatic Arthritis
phase
marketed
approved
2019-04-23
Data sources
openFDA · ClinicalTrials.gov
last refreshed 27m ago
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