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  1. pharmadog
  2. ›drugs
  3. ›Zynyz
drug · antibody
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retifanlimab

Marketedupdated 3mo ago
by $INCY INCYTE CORP🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 5
  • tagApproval20 co-mentions · 5 sources
  • drugZYNYZ20 co-mentions · 5 sources
  • company$INCYINCYTE CORP11 co-mentions · 6 sources
  • tagOncology6 co-mentions · 1 sources
  • tagSmall Molecule1 co-mentions · 1 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 16 investigational indications.

targets

Programmed cell death protein 1

all catalysts(6)

approval · 5
Mar 22, 2023
approval
$INCY122.22+1.71%
3y ago
ZYNYZ (RETIFANLIMAB-DLWR) — FDA approval
retifanlimab
→
Apr 22, 2024
approval
$INCY122.22+1.71%
2y ago
ZYNYZ (RETIFANLIMAB-DLWR) — FDA approval
retifanlimab
→
May 15, 2025
approval
$INCY122.22+1.71%
1y ago
ZYNYZ (RETIFANLIMAB-DLWR) — FDA approval
retifanlimab
→
Dec 17, 2025
approval
$INCY122.22+1.71%
8mo ago
ZYNYZ (RETIFANLIMAB-DLWR) — FDA approval
retifanlimab
→
Mar 30, 2026
approval
$INCY122.22+1.71%
5mo ago
ZYNYZ (RETIFANLIMAB-DLWR) — FDA approval
retifanlimab
→
phase 3 initiation · 1
Apr 29, 2026
phase 3 initiation
$INCY122.22+1.71%
4mo ago
Incyte Corp — retifanlimab (Phase III Trial Initiation)
retifanlimab
→

Trials studying retifanlimab

  • phase3Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.recruitingn=404
  • phase1A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutationrecruitingn=710
  • phase1Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastomaactive not recruitingn=27
  • EP1A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Gliomarecruitingn=24
  • phase2Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcomarecruitingn=98
  • phase3Platinum-Based Chemotherapy With/Without INCMGA00012, an Anti-PD-1 Antibody, in Non-Small Cell Lung Canceractive not recruitingn=583
  • phase2Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neckactive not recruitingn=176
  • phase2Combination Study of SV-BR-1-GM With Retifanlimabcompletedn=36
more trials →

News(4)

  • Scholar Rock ditches Novo’s legacy Catalent plant in FDA refiling of SMA drug
    Scholar Rock has dropped Novo Nordisk’s troubled Catalent facility as a contract manufacturer in its FDA refiling for apitegromab, a spinal muscular atrophy candidate, after a recent inspection of…
    fiercebiotech · 7d ago
  • Incyte ditches phase 1-stage JAK inhibitor to pursue next-gen options
    Incyte has ditched a JAK2 inhibitor in phase 1 development for a rare blood cancer in favor of “next-generation” replacements.
    fiercebiotech · 20d ago
  • Immunotherapy Advances in Upfront SCAC Expose Need for Better Second-Line Strategies
    Aparna R. Parikh, MD, emphasizes the feasibility of immunotherapy trials in SCAC and the need for better treatment options in the second line and beyond.
    onclive · 3mo ago
  • Dr Parikh on the Feasibility and Importance of Immunotherapy Trials in Anal Cancer
    Aparna R. Parikh, MD, discusses how trials like PODIUM-303 are reshaping the treatment paradigm for squamous cell anal carcinomas.
    onclive · 3mo ago
brand
Zynyz
trade names
Zynyz
generic
retifanlimab-dlwr
MOA
Programmed cell death protein 1 antagonist
indication
Squamous Non-Small Cell Lung Cancer
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 32m ago
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