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  1. pharmadog
  2. ›drugs
  3. ›Ultomiris
drug · antibody
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ravulizumab LA

Marketedupdated 5mo ago
by Alexion Pharmaceuticals Inc🔗 ChEMBL
Approved
annual revenue · 2024–2024peak $3.9B
2024: $3.9B2024$3.9B
community read0 votes

🐶 often sniffed alongside

top 1
  • tagApproval72 co-mentions · 18 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for hemolytic-uremic syndrome and paroxysmal nocturnal hemoglobinuria and 11 investigational indications.

targets

Complement C5

all catalysts(0)

nothing on the calendar yet

Trials studying ravulizumab LA

  • —Real-life Treatment Outcomes of Ravulizumab in PNHactive not recruitingn=64
  • —Ravulizumab Outcomes in Polish Patients With aHUSrecruitingn=80
  • phase3Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD)recruitingn=19
  • phase3ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKEcompletedn=544
  • phase3Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantationrecruitingn=450
  • —Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravisrecruitingn=50
  • —Real Life Use of Ravulizumab in Italian Patients With Paroxysmal Nocturnal Hemoglobinuriacompletedn=120
  • phase3A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatmentactive not recruitingn=202

News(5)

  • AstraZeneca pulls plug on late-stage lung cancer trial, taking another clinical blow
    AstraZeneca will push through with its other Phase 3 studies for volrustomig, including in cervical cancer and mesothelioma.
    biospace · 1mo ago
  • AstraZeneca pulls plug on late-stage lung cancer trial, taking another clinical blow
    AstraZeneca will push through with its other Phase 3 studies for volrustomig, including in cervical cancer and mesothelioma.
    biospace · 1mo ago
  • FDA scientists question Capricor data; Legend CEO steps down
    Capricor shares lost much of their value ahead of a high-stakes advisory committee meeting. Elsewhere, Ying Huang’s resignation extended a stock slide for Legend and AstraZeneca disclosed more pipe…
    biopharma_dive · 2mo ago
  • AstraZeneca has no plans to ramp up dealmaking in wake of Wainua failure
    AstraZeneca remains "very much on track" to hit its 2030 goal of reaching $80 billion in revenue despite the recent late-stage failure of Wainua in ATTR-cardiomyopathy, CEO Pascal Soriot said durin…
    biospace · 2mo ago
  • Updated: AstraZeneca foresees blockbuster sales for Claudin 18.2 ADC, but Ultomiris flops in rare disease
    AstraZeneca said Monday that a key late-stage trial of its Claudin 18.2-targeting ADC in stomach cancer had succeeded, albeit with a caveat — but another Phase 3 trial of Ultomiris yielded subpar r…
    endpoints · 2mo ago
brand
Ultomiris
trade names
Ultomiris
generic
ravulizumab
MOA
Complement C5 inhibitor
indication
Delayed Graft Function (DGF)
phase
marketed
approved
2018-12-21
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 27m ago
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