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  1. pharmadog
  2. ›drugs
  3. ›PROGESTERONE
drug · small molecule
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PROGESTERONE

Marketedupdated 3mo ago
by IBSA Institut Biochimique SA🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval77 co-mentions · 22 sources
  • tagSmall Molecule36 co-mentions · 19 sources
  • drugESTRING4 co-mentions · 2 sources
  • companyEugia US LLC2 co-mentions · 1 sources
  • tagRecall2 co-mentions · 2 sources
  • companyAll India Institute of Medical Sciences1 co-mentions · 1 sources
  • companyUniversity of Utah1 co-mentions · 1 sources
  • tagWomen's Health1 co-mentions · 1 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 4 approved and 35 investigational indications.

targets

Progesterone receptor

all catalysts(3)

approval · 2
Sep 19, 2025
approval
11mo ago
PROGESTERONE — FDA approval
PROGESTERONE
→
Apr 8, 2026
approval
4mo ago
PROGESTERONE — FDA approval
PROGESTERONE
→
phase 2 3 completion · 1
Apr 26, 2026
phase 2 3 completion
4mo ago
All India Institute of Medical Sciences — progesterone (Phase II/III Trial Completion)
PROGESTERONE
→

Trials studying PROGESTERONE

  • phase3A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)recruitingn=266
  • phase3Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Monthswithdrawn
  • phase3Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.active not recruitingn=688
  • phase4Exogenous Progesterone as Ovulation Triggernot yet recruitingn=10
  • phase3Individualized Prolonged Luteal Support After Fresh Embryo Transfer in Women With Low Progesteronenot yet recruitingn=214
  • phase1First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiencyrecruitingn=20
  • phase2A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)recruitingn=250
  • phase4Menopausal HT for Women Living With HIV (HoT)not yet recruitingn=105
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Feb 3, 2029
~2.5 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (3)

  • Jan 21, 2030method-of-use (U-2810)US 85802933.4y
  • Feb 3, 2029formulationUS 105375842.5y
  • Feb 3, 2029method-of-use (U-2810)US 105489042.5y

FDA exclusivities (1)

  • Mar 22, 2026CGTCGT

News(2)

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brand
PROGESTERONE
trade names
Crinone, Cyclogest, Endometrin, Lutigest, Milprosa, Prochieve
generic
PROGESTERONE
MOA
Progesterone receptor agonist
indication
Female Infertility
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 28m ago
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