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  1. pharmadog
  2. ›drugs
  3. ›Redemplo
drug · oligonucleotide
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plozasiran sodium

Marketedupdated 3mo ago
by $ARWR ARROWHEAD PHARMACEUTICALS, INC.🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 2
  • tagApproval4 co-mentions · 1 sources
  • drugREDEMPLO4 co-mentions · 1 sources

Oligonucleotide drug with a maximum clinical stage of Unknown (across all indications), with 3 investigational indications.

all catalysts(1)

approval · 1
Nov 18, 2025
approval
$ARWR89.95+1.83%
9mo ago
REDEMPLO (PLOZASIRAN SODIUM) — FDA approval
plozasiran sodium
→

Patent cliff

source: FDA Orange Book
first barrier falls
Mar 7, 2037
~10.6 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (5)

  • Sep 10, 2038compositionUS 10597657
  • Sep 10, 2038compositionUS 11214801
  • Sep 10, 2038compositionUS 12365899
  • Mar 7, 2037compositionUS 10294474
  • Mar 7, 2037compositionUS 11174481

News(5)

  • ‘Significant’ demand for Revolution drug; Intellia pinpoints liver toxicity culprit
    Early indicators from a compassionate use plan led analysts to hike projections for daraxonrasib. Elsewhere, Intellia believes it’s answered a key safety question and Arrowhead moved to catch a rival.
    biopharma_dive · 4d ago
  • FDA panel confronting peptide controversy
    Today's biotech news features the FDA weighing the fate of peptides; approvals for RevMed, GSK; and data on Lilly's "triple-G."
    stat · 19d ago
  • Arrowhead hits ‘best-case scenario’ with latest results for fat-lowering drug
    To analysts, the drug’s apparent safety and effects on both triglyceride levels and pancreatitis cases should make it competitive with a rival Ionis therapy.
    biopharma_dive · 20d ago
  • Arrowhead’s gene silencer competitive with Ionis’ in triglyceride disease
    Arrowhead Pharmaceuticals’ lipid-lowering drug has hit in two late-stage trials that could expand its use into a much wider population. Data shared Wednesday showed that Arrowhead’s gene silencer R…
    endpoints · 20d ago
  • Arrowhead puts pressure on Ionis with positive data for triglyceride lowering drug
    With Phase 3 data showing what analysts called a “potentially best-in-class profile,” Arrowhead Pharmaceuticals plans to submit for FDA approval of plozasiran by the end of the year—hoping to follo…
    biospace · 20d ago
brand
Redemplo
generic
plozasiran sodium
MOA
12.1 Mechanism of Action Plozasiran is a siRNA conjugated with GalNAc that degrades the apoC-III mRNA through the RNA interference mechanism resulting in reduced levels of hepatic and serum apoC-III protein. Reduction of apoC- III protein leads to increased clearance of serum triglycerides.
indication
Hypertriglyceridemia
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 30m ago
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