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  1. pharmadog
  2. ›drugs
  3. ›Pemfexy
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pemetrexed

Marketedupdated 5mo ago
by Eagle Pharmaceuticals Inc
Approved
community read0 votes

🐶 often sniffed alongside

top 5
  • tagApproval18 co-mentions · 9 sources
  • drugAXTLE8 co-mentions · 4 sources
  • drugAlimta5 co-mentions · 5 sources
  • drugPEMETREXED DISODIUM5 co-mentions · 5 sources
  • drugPemetrexed Disodium Intas5 co-mentions · 5 sources

indications

investigational
NSCLC

all catalysts(0)

nothing on the calendar yet

Trials studying pemetrexed

  • phase3A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)recruitingn=680
  • phase3Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatmentactive not recruitingn=428
  • phase3Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]completedn=1,280
  • phase3An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)active not recruitingn=49
  • phase1A Study of ASP3082 in Adults With Advanced Solid Tumorsrecruitingn=681
  • phase2Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterationsrecruitingn=252
  • phase3A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failureactive not recruitingn=776
  • phase1Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Canceractive not recruitingn=751

Patent cliff

source: FDA Orange Book
first barrier falls
Mar 26, 2035
~8.5 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (6)

  • Feb 19, 2036formulationUS 11793813
  • Feb 19, 2036method-of-use (U-4248)US 12115164
  • Oct 28, 2035compositionUS 9604990
  • Mar 26, 2035formulationUS 11147817
  • Mar 26, 2035formulationUS 11147817
  • Mar 26, 2035formulationUS 11147817

News(0)

no news has mentioned this drug yet

brand
Pemfexy
generic
pemetrexed [INN]
indication
Malignant Pleural Mesothelioma
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 1h ago
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