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  1. pharmadog
  2. ›drugs
  3. ›Krystexxa
drug
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pegloticase

Marketedupdated 5mo ago
by Horizon Therapeutics USA Inc
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Trials studying pegloticase

  • phase4A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Goutcompletedn=306
  • phase3A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Goutrecruitingn=270
  • phase4Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexatecompletedn=191
  • phase4A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)completedn=50
  • phase4Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapycompletedn=11
  • phase4Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplantcompletedn=20
  • phase4Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Goutcompletedn=152
  • phase4Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Goutcompletedn=14

News(3)

  • Amgen’s Horizon-acquired fusion protein eases Sjögren's severity in ph. 3 win
    An investigational drug for the autoimmune condition Sjögren's disease has scored a phase 3 win for Amgen, marking a positive sign for the Horizon Therapeutics-acquired pipeline that has so far str…
    fiercebiotech · 11d ago
  • Crystalys nets $130M more to push gout drug through late-stage tests
    The startup has a broad global development program underway — and the support of more than 20 investment firms — for a treatment that’s approved in many Asian countries but isn’t yet available in t…
    biopharma_dive · 2mo ago
  • Crystalys mines $130M series B to push gout drug through phase 3
    Crystalys Therapeutics has raised $130 million in series B financing to advance the development of its gout drug dotinurad and prepare for a potential commercial launch.
    fiercebiotech · 2mo ago
brand
Krystexxa
generic
pegloticase
indication
Gouty Arthritis (Gout)
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 2h ago
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