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  1. pharmadog
  2. ›drugs
  3. ›PAXLOVID (COPACKAGED)
drug · small molecule
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PAXLOVID (COPACKAGED)

Marketedupdated 3mo ago
by $PFE PFIZER INC🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval28 co-mentions · 7 sources
  • drugnirmatrelvir + ritonavir14 co-mentions · 7 sources
  • tagSmall Molecule14 co-mentions · 7 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 4 investigational indications.

targets

Replicase polyprotein 1a

all catalysts(7)

approval · 7
May 25, 2023
approval
$PFE26.87+0.30%
3y ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Sep 12, 2024
approval
$PFE26.87+0.30%
2y ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Nov 19, 2024
approval
$PFE26.87+0.30%
2y ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Jan 31, 2025
approval
$PFE26.87+0.30%
2y ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Feb 12, 2025
approval
$PFE26.87+0.30%
2y ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Feb 11, 2026
approval
$PFE26.87+0.30%
6mo ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→
Feb 11, 2026
approval
$PFE26.87+0.30%
6mo ago
PAXLOVID (COPACKAGED) (NIRMATRELVIR) — FDA approval
PAXLOVID (COPACKAGED)
→

Trials studying PAXLOVID (COPACKAGED)

  • phase1A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19terminatedn=25
  • —A Study to Learn About the Study Medicine Paxlovid (Nirmatrelvir + Ritonavir) in Adults Aged 60 and Older Living in Korean Long-term Care Hospitals Who Have COVID-19completedn=937
  • —A US Study to Look at Loss of Work and Healthcare Costs for People Affected With Mild-to-moderate COVID 19 Who Have High Chances of the Disease Becoming Severecompletedn=131,005
  • phase1A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participantswithdrawn
  • —A Study to Learn How Paxlovid [Nirmatrelvir-ritonavir/PF-07321332] Works in COVID-19 Patients Who Are Elderly or Have Medical Conditions.active not recruitingn=99,000
  • phase2Paxlovid for Treatment of Long Covidcompletedn=168
  • —A Study to Learn About PAXLOVID (a Commercial Medicine) In People With COVID-19completedn=3,346
  • —A Study to Learn About the Use of Paxlovid in Patients With COVID-19 in the Kingdom of Bahrain.completedn=3,011
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Jan 31, 2028
~1.5 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Oct 31, 2041method-of-use (U-3629)US 11541034
  • Aug 5, 2041compositionUS 11351149

FDA exclusivities (2)

  • May 25, 2028NCENew Chemical Entity (5y)1.8y
  • Jan 31, 2028D-195New Indication (3y)1.5y

News(0)

no news has mentioned this drug yet

brand
PAXLOVID (COPACKAGED)
trade names
Nirmatrelvir component of paxlovid
generic
NIRMATRELVIR
MOA
SARS coronavirus 3C-like proteinase inhibitor
indication
kidney disease
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 12m ago
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